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Þorsteinn Loftsson - Prófessor emeritus

Þorsteinn Loftsson

–

Heilbrigðisvísindasvið

Þorsteinn Loftsson

Prófessor emeritus

Aðsetur
Hagi / Ha-313
Sími
5254464
Tölvupóstur
thorstlo [hjá] hi.is

Starfseining
Lyfjafræðideild kennsla/rekstur
Ritaskrá
Þorsteinn Loftsson - ritaskrá

Ferilskrá
Þorsteinn Loftsson - ferilskrá
ORCID vefsíða
https://orcid.org/0000-0002-9439-1553
Rannsóknagátt – Þorsteinn Loftsson

Útgefið efni

2024

The application of cyclodextrins in drug solubilization and stabilization of nanoparticles for drug delivery and biomedical applicationsInternational Journal of Pharmaceutics
Antimicrobial Preservatives in Cyclodextrin-Containing Drug FormulationsPharmaceutics
New Improved cGMP Analogues to Target Rod Photoreceptor DegenerationJournal of Medicinal Chemistry
Drug-like properties of tyrosine kinase inhibitors in ophthalmologyInternational Journal of Pharmaceutics
Aqueous eye drop formulationsAnnales Pharmaceutiques Francaises
Drug-like properties and topical delivery of rapalogs and tacrolimus in ophthalmologyJournal of Drug Delivery Science and Technology

2023

A promising synthetic citric crosslinked β-cyclodextrin derivative for antifungal drugsInternational Journal of Pharmaceutics
Topical dexamethasone delivery to the retinaJournal of Drug Delivery Science and Technology
Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspensionActa Ophthalmologica
Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous SolutionsMaterials
Crystal Modifications of a Cyclic Guanosine Phosphorothioate Analogue, a Drug Candidate for Retinal NeurodegenerationsChemistryOpen
Voriconazole Eye DropsInternational Journal of Molecular Sciences
Celecoxib/Cyclodextrin Eye Drop MicrosuspensionsPharmaceutics
Tacrolimus/hydroxypropyl-β-cyclodextrin-loaded nanoemulsions stabilized by Zein-Soluplus® nanoparticles for retinal diseasesJournal of Drug Delivery Science and Technology

2022

Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular DeliveryPharmaceutics
Topical noninvasive retinal drug delivery of a tyrosine kinase inhibitorActa Ophthalmologica
Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular DeliveryMolecules
Topical drug delivery to the retinaExpert Opinion on Drug Delivery
Stabilization and solubilization of difluprednate in aqueous cyclodextrin solution and its characterization for ophthalmic deliveryJournal of Drug Delivery Science and Technology
Preformulation studies of dovitinib free baseInternational Journal of Pharmaceutics
Angiotensin converting enzyme inhibitors/cyclodextrin inclusion complexesJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and Drug Membrane Permeation: Thermodynamic ConsiderationsJournal of Pharmaceutical Sciences
A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal DeliveryPharmaceuticals
Self-assembled γ-cyclodextrin as nanocarriers for enhanced ocular drug bioavailabilityInternational Journal of Pharmaceutics
Structural Characterization Study of a Lipid Nanocapsule Formulation Intended for Drug Delivery Applications Using Small-Angle Scattering TechniquesMolecular Pharmaceutics
Aqueous Prostaglandin Eye Drop FormulationsPharmaceutics
Integration of cyclodextrins and associated toxicitiesCarbohydrate Polymers

2021

Age-related ocular conditionsInternational Journal of Pharmaceutics
Aqueous eye drops containing drug/cyclodextrin nanoparticles deliver therapeutic drug concentrations to both anterior and posterior segmentActa Ophthalmologica
Cyclodextrins in parenteral formulationsJournal of Pharmaceutical Sciences
Topical drug delivery to the posterior segment of the eye: Thermodynamic considerationsInternational Journal of Pharmaceutics
1,4-Benzodiazepines: Chemical stability and cyclodextrin solubilizationJournal of Drug Delivery Science and Technology
Bio-distribution and pharmacokinetics of topically administered γ-cyclodextrin based eye drops in rabbitsPharmaceuticals
Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery – A reviewInternational Journal of Pharmaceutics
Solubility and stability of cediranib maleateJournal of Drug Delivery Science and Technology
Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug FormulationsMolecules
Formulation development and upscaling of lipid nanocapsules as a drug delivery system for a novel cyclic GMP analogue intended for retinal drug deliveryInternational Journal of Pharmaceutics
Effect of Soluplus^® on γ-cyclodextrin solubilization of irbesartan and candesartan and their nanoaggregates formationPharmaceutical Development and Technology
Aggregate Determination by Permeation Technique
Effect of salt formation on γ-cyclodextrin solubilization of irbesartan and candesartan and the chemical stability of their ternary complexesJournal of Drug Delivery Science and Technology
Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye dropsActa Ophthalmologica

2020

Aqueous solubility of kinase inhibitorsJournal of Drug Delivery Science and Technology
In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye InflammationNanomaterials
Antifungal activity of econazole nitrate/cyclodextrin complex: Effect of pH and formation of complex aggregatesInternational Journal of Pharmaceutics
Solubilization and in vitro permeation of dovitinib/cyclodextrin complexes and their aggregatesJournal of Inclusion Phenomena and Macrocyclic Chemistry
Effect of porcine pancreatic α-amylase on dexamethasone release from aqueous solution containing natural γ-cyclodextrinInternational Journal of Pharmaceutics
Stability characterization, kinetics and mechanism of tacrolimus degradation in cyclodextrin solutionsInternational Journal of Pharmaceutics
Poorly soluble drugsInternational Journal of Pharmaceutics
Can postoperative dexamethasone nanoparticle eye drops replace mitomycin C in trabeculectomy?Acta Ophthalmologica
Aqueous solubility of kinase inhibitorsJournal of Inclusion Phenomena and Macrocyclic Chemistry
Free Fatty Acids from Fish Oil Inactivate SARS-CoV-2Journal of SARS-CoV-2 and Coronavirus Disease
Self-assembly of cyclodextrin complexes: detection, obstacles and benefitsPharmazie
Characterization and Evaluation of Ternary Complexes of Ascorbic Acid with γ-Cyclodextrin and Poly(vinyl Alcohol)International Journal of Molecular Sciences
Aqueous solubility of kinase inhibitorsJournal of Drug Delivery Science and Technology

2019

Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of NatamycinNanomaterials
Development of celecoxib eye drop solution and microsuspension: a comparative investigation of binary and ternary cyclodextrin complexesCarbohydrate Polymers
Drug delivery to retinal photoreceptorsDrug Discovery Today
Interaction of native cyclodextrins and their hydroxypropylated derivatives with parabens in aqueous solutions. Part 2: evaluation of paraben/cyclodextrin complex aggregationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Interaction of Native Cyclodextrins and Their Hydroxypropylated Derivatives with Carbamazepine in Aqueous Solution. Evaluation of Inclusion Complexes and Aggregates FormationACS Omega
Interaction of native cyclodextrins and their hydroxypropylated derivatives with parabens in aqueous solutions. Part 1: evaluation of inclusion complexesJournal of Inclusion Phenomena and Macrocyclic Chemistry
Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop FormulationMaterials
Self-association of cyclodextrins and cyclodextrin complexes in aqueous solutionsInternational Journal of Pharmaceutics

2018

Cyclodextrins: structure, physicochemical properties and pharmaceutical applicationsInternational Journal of Pharmaceutics
Topical drug delivery to the posterior segment of the eyeJournal of Drug Delivery Science and Technology
Cyclodextrin solubilization of celecoxib: Solid and solution state characterizationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Effect of β- and γ-cyclodextrins and their methylated derivatives on the degradation rate of benzylpenicillinJournal of Inclusion Phenomena and Macrocyclic Chemistry
Solubility of Cyclodextrins and Drug/Cyclodextrin ComplexesMolecules
Novel excipients – Regulatory challenges and perspectives – The EU insightInternational Journal of Pharmaceutics
Disruption of α- and γ-cyclodextrin aggregates promoted by chaotropic agent (urea)Journal of Drug Delivery Science and Technology
2-Hydroxypropyl-β-Cyclodextrin Aggregates: Identification and Development of Analytical TechniquesMaterials
Topical drug delivery to the posterior segment of the eyeJournal of Drug Delivery Science and Technology
Self-assembled cyclodextrin-based nanoparticles for meropenem stabilizationJournal of Drug Delivery Science and Technology
Self-Assembly of α-Cyclodextrin and β-CyclodextrinJournal of Pharmaceutical Sciences
Cyclodextrins-based formulations: a non-invasive platform for targeted drug deliveryBasic and Clinical Pharmacology and Toxicology
Inclusion complexes of p-hydroxybenzoic acid esters and γ-cyclodextrinJournal of Inclusion Phenomena and Macrocyclic Chemistry
Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: An explorative study in healthy volunteersEuropean Journal of Clinical Pharmacology
Self-assemble of α-cyclodextrin and β-cyclodextrin: Identification and development of analytical techniquesJournal of Pharmacological Sciences

2017

Soluble 1:1 complexes and insoluble 3:2 complexes – Understanding the phase-solubility diagram of hydrocortisone and γ-cyclodextrinInternational Journal of Pharmaceutics
Crystallographic and theoretical studies of inclusion complex of β-cyclodextrin with fentanylInternational Journal of Pharmaceutics
Cyclodextrin complexes of a globular protein and a lipophilic oligopeptide: the effect of structure and physicochemical propertiesPharmazie
Evaluation of γ-cyclodextrin effect on permeation of lipophilic drugs: application of cellophane/fused octanol membranePharmaceutical Development and Technology
Editorial Special edition of International Journal of Pharmaceutics in honor of Professor Dominique DuchêneInternational Journal of Pharmaceutics
Formulations and toxicologic in vivo studies of aqueous cyclosporin A eye drops with cyclodextrin nanoparticlesInternational Journal of Pharmaceutics
Drug solubilization by complexationInternational Journal of Pharmaceutics
Effects of cyclodextrins on the chemical stability of drugsInternational Journal of Pharmaceutics
γ-CyclodextrinInternational Journal of Pharmaceutics
Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eyeInternational Journal of Pharmaceutics

2016

Effect of cyclodextrins on the degradation rate of benzylpenicillinPharmazie
Cyclodextrin-poloxamer aggregates as nanocarriers in eye drop formulations: dexamethasone and amphotericin BDrug Development and Industrial Pharmacy
A Tribute to Dr. Marcus E. BrewsterJournal of Pharmaceutical Sciences
Self-assembly of cyclodextrins and their complexes in aqueous solutionsJournal of Pharmacological Sciences
Microspheres and nanotechnology for drug delivery, in Retinal Pharmacotherapy
The self-assemble of natural cyclodextrins in aqueous solutions: application of miniature permeation studies for critical aggregation concentration (cac) determinationsInternational Journal of Pharmaceutics
Interaction of fentanyl with various cyclodextrins in aqueous solutionsJournal of Pharmacy and Pharmacology
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in childrenActa Paediatrica, International Journal of Paediatrics
Topical Formulation Comprising Fatty Acid Extract from Cod Liver Oil: Development, Evaluation and Stability StudiesMarine Drugs
Fatty acids from marine lipids: biological activity, formulation and stability of fatty acids from cod-liver oilJournal of Drug Delivery Science and Technology
Pharmacokinetics of cyclodextrins and drugs after oral and parenteral administration of drug/cyclodextrin complexesJournal of Pharmacy and Pharmacology
Cyclodextrin-based telmisartan ophthalmic suspension: Formulation development for water-insoluble drugsInternational Journal of Pharmaceutics
Fatty acids from marine lipidsJournal of Drug Delivery Science and Technology

2015

A new approach for quantitative determination of γ-cyclodextrin in aqueous solutions: application in aggregate determinations and solubility in hydrocortisone/γ-cyclodextrin inclusion complexJournal of Pharmacy and Pharmaceutical Sciences
Microspheres and nanotechnology for drug deliveryDevelopments in Ophthalmology
Development of eye drops containing antihypertensive drugsPharmaceutical Development and Technology
Electroblowing and electrospinning of fibrous diclofenac sodium cyclodextrin complex-based reconstitution injectionJournal of Drug Delivery Science and Technology
Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy.Frontline Gastroenterology
Formation and stability assessment of self-assembled nanoparticles from large Mw chitosan and sulfobutylether-β-cyclodextrinJournal of Drug Delivery Science and Technology
Formulation of drug-cyclodextrin complexes
Topical dexamethasone γ-cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedemaActa Ophthalmologica
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists
Development of a cyclodextrin-based aqueous cyclosporin A eye drop formulationsInternational Journal of Pharmaceutics
Excipient pharmacokinetics and profilingInternational Journal of Pharmaceutics

2014

Effect of γ-cyclodextrin on solubilization and complexation of irbesartanInternational Journal of Pharmaceutics
Surface activity and self-aggregation ability of three cationic quaternized aminocalix[4]arenesJournal of Inclusion Phenomena and Macrocyclic Chemistry
Drug Stability for Pharmaceutical Scientists
Dorzolamide cyclodextrin nanoparticle suspension eye drops and trusopt in rabbitJournal of Ocular Pharmacology and Therapeutics
Self-assembled cyclodextrin nanoparticles and drug deliveryJournal of Inclusion Phenomena and Macrocyclic Chemistry
Sulfobutylether-β-cyclodextrin/chitosan nano- and microparticles and their physicochemical characteristicsInternational Journal of Pharmaceutics
γ-cyclodextrin nanoparticle eye drops with dorzolamideJournal of Ocular Pharmacology and Therapeutics
Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrinsJournal of Inclusion Phenomena and Macrocyclic Chemistry
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluidActa Ophthalmologica

2013

CyclodextrinsInternational Journal of Pharmaceutics
Triclosan-loaded with high encapsulation efficiency into PLA nanoparticles coated with β-cyclodextrin polymerJournal of Inclusion Phenomena and Macrocyclic Chemistry
For the special IJP issue "Poorly soluble drugs"International Journal of Pharmaceutics
Drug solubilization and stabilization of cyclodextrin drug carriers
Dextran-based cyclodextrin polymers: Their solubilizing effect and self-associationCarbohydrate Polymers
Cationic quaternized aminocalix[4]arenes: cytotoxicity, haemolytic and antibacterial activitiesInternational Journal of Pharmaceutics
A permeation method for detection of self-aggregation of doxorubicin in aqueous environmentInternational Journal of Pharmaceutics
Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrinsJournal of Inclusion Phenomena and Macrocyclic Chemistry
Antifungal drug solubilizing activity and self-aggregation ability of cationic aminocalix[4]arene in comparison to SBEβCD: effect of addition of water-soluble polymerJournal of Inclusion Phenomena and Macrocyclic Chemistry
Dexamethasone eye drops containing γ-cyclodextrin-based nanogelsInternational Journal of Pharmaceutics
CyclodextrinsInternational Journal of Pharmaceutics
Drug Solubilization and Stabilization by Cyclodextrin Drug Carriers
Encapsulation of drug molecules into Calix[n]arene Nanobaskets. Role of Aminocalix[n]arenes in biopharmaceutical fieldJournal of Pharmaceutical Sciences

2012

Drug permeation through biomembranes: Cyclodextrins and the unstirred water layerPharmazie
Self-assembly of cyclodextrins: Formation of cyclodextrin polymer based nanoparticlesJournal of Drug Delivery Science and Technology
Cyclodextrins as functional excipients: Methods to enhance complexation efficiencyJournal of Pharmaceutical Sciences
Cyclodextrin-based nanogels for pharmaceutical and biomedical applicationsInternational Journal of Pharmaceutics
The effect of parenterally administered cyclodextrins on the pharmacokinetics of coadministered drugsJournal of Pharmaceutical Sciences
Complex Formation
Topical drug delivery to the eyeActa Ophthalmologica
Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug deliveryCarbohydrate Polymers
Clinical trialMarine Drugs

2011

Preface: First European cyclodextrin conferenceJournal of Inclusion Phenomena and Macrocyclic Chemistry
Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edemaInvestigative Ophthalmology and Visual Science
Self-assembly of cyclodextrin complexes: Effect of temperature, agitation and media composition on aggregationInternational Journal of Pharmaceutics
Self-assembly of cyclodextrins: The effect of the guest moleculeInternational Journal of Pharmaceutics
Drug loading in cyclodextrin polymersJournal of Inclusion Phenomena and Macrocyclic Chemistry
Self-assembly of cyclodextrin complexes: the effect of the guest moleculeInternational Journal of Pharmaceutics
Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexesInternational Journal of Pharmaceutics
Pharmaceutical applications of cyclodextrins: Effects on drug permeation through biological membranesJournal of Pharmacy and Pharmacology
Cyclodextrin-Based Hydrogels
Cyclodextrin enhanced drug delivery through mucus membranes
Topical dexamethasone-cyclodextrin nanoparticle eye drops improve visual acuity and reduce retinal thickness in diabetic macular edemaInvestigative Ophthalmology and Visual Science
Evaluation of sugammadex self-associationInternational Journal of Pharmaceutics
Drug/cyclodextrin: Beyond inclusion complexationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrin-Enhanced Drug Delivery through Mucous Membranes

2010

Effect of self-aggregation of γ-cyclodextrin on drug solubilizationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Solubility and permeability of steroids in water in the presence of potassium halidesDie Pharmazie
Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV-Vis titrationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Effects of cogrinding with β-cyclodextrin on the solid state fentanylJournal of Pharmaceutical Sciences
Self-assembled cyclodextrin aggregates and nanoparticlesInternational Journal of Pharmaceutics
γ-Cyclodextrin hydrogels and semi-interpenetrating networks for sustained delivery of dexamethasoneCarbohydrate Polymers
Cyclodextrins as solubilizers: Formation of complex aggregatesJournal of Pharmaceutical Sciences
Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbitsActa Ophthalmologica
Pharmaceutical applications of cyclodextrins: Basic science and product developmentJournal of Pharmacy and Pharmacology
Parenteral delivery of HPβCD: Effects on drug-HSA bindingAAPS PharmSciTech
γCD/HPγCD mixtures as solubilizerJournal of Pharmacy and Pharmaceutical Sciences
Evaluation of a cationic calix[4]arene: Solubilization and self-aggregation abilityInternational Journal of Pharmaceutics
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugsEuropean Journal of Pharmaceutics and Biopharmaceutics
Aqueous solubility and true solutionsPharmazie

2009

Drug targeting to the hair follicles: A cyclodextrin-based drug deliveryAAPS PharmSciTech
Fish skin as a model membrane: Structure and characteristicsJournal of Pharmacy and Pharmacology
CDs as solubilizers: Effects of excipients and competing drugsInternational Journal of Pharmaceutics
Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equationGraefe's Archive for Clinical and Experimental Ophthalmology
Cyclodextrins as solubilizers: effects of excipients and competing drugsInternational Journal of Pharmaceutics
Cyclodextrins and their use in pharmacy and cosmetology | Les cyclodextrines et leurs utilisations en pharmacie et cosmétologieS.T.P. Pharma Pratiques
Crystal structure of fentanyl baseX-ray Structure Analysis Online

2008

Carvedilol: Solubilization and cyclodextrin complexation: A technical noteAAPS PharmSciTech
Physicochemical properties of water and its effect on drug delivery. A commentaryInternational Journal of Pharmaceutics
Comparative interaction of 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin with itraconazole: Phase-solubility behavior and stabilization of supersaturated drug solutionsEuropean Journal of Pharmaceutical Sciences
γCD/HPγCD: Synergistic solubilizationInternational Journal of Pharmaceutics
Topical drug delivery to the posterior segment of the eyePharmazie

2007

Development of octanol membranes for drug screeningJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrin microparticles for drug delivery to the posterior segment of the eyeJournal of Pharmacy and Pharmacology
Cyclodextrins as pharmaccutical solubilizers.Advanced Drug Delivery Reviews
Cyclodextrins in ocular drug delivery: theoretinal basis with dexamethasone as a sample drug.Journal of Drug Delivery Science and Technology
The complexation efficiencyJournal of Inclusion Phenomena and Macrocyclic Chemistry
Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrinsInternational Journal of Pharmaceutics
Studies on Curcumin and Curcuminoids XXXI: Symmetric and Asymmetric curcuminoids: Their stability, activity and complexation with cyclodextrin.International Journal of Pharmaceutics
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eyeActa Ophthalmologica Scandinavica
The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines.
Cyclodextrins and the liquid-liquid phase distributionof progesterone, estrone and prednicarbate.Journal of Inclusion Phenomena and Macrocycle Chemistry
Effects of cyclodextrins on drug delivery through biological membranesJournal of Pharmaceutical Sciences
Effects of various cyclodextrins on the stability of freeze-dried lactate dehydrogenaseJournal of Pharmaceutical Sciences
Dexamethasone delivery to posterior segment of the eyeJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and the liquid-liquid phase distribution of progesterone, estrone and prednicarbateJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and their pharmaceutical applicationsInternational Journal of Pharmaceutics
Studies on curcumin and curcuminoids. XXXI. Symmetric and asymmetric curcuminoidsInternational Journal of Pharmaceutics
Dexamethasone delivery to posterior segment of the eyeJournal of Inclusion Phenomena and Macrocyclic Chemistry
Antibacterial activity of methylated chitosan and chitooligomer derivativesEuropean Polymer Journal

2006

Unexpected discrepancy between bioavailability and pharmacodynamic effect in the CNS when comparing two nasal spraysJournal of Pharmacy and Pharmacology
Aquavitae. Áhrif vatns á lyfjaþróun
The pharmaceutical education in IcelandQuality Assurance in Pharmacy Education
Development and evaluation of an artificial membrane for determination of drug availabilityInternational Journal of Pharmaceutics
Investigation of soft long chain quaternary ammonium compounds as co-factors to enhance in vitro gene deliveryPharmazie
The Stokes-Einstein equation and the physiological effects of vitreous surgeryActa Ophthalmologica Scandinavica
Comparison of 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postoperative inflammationGraefe's Archive for Clinical and Experimental Ophthalmology
Determination of aqueous solubility by heating and equilibration: A technical noteAAPS PharmSciTech
Ocular powderJournal of Ocular Pharmacology and Therapeutics
Assessment of mucoadhesion by a resonant mirror biosensorInternational Journal of Pharmaceutics
Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranesPharmazie
Intranasal midazolam: A comparison of two delivery devices in human volunteersJournal of Pharmacy and Pharmacology

2005

Evaluation of cyclodextrin solubilization of drugsInternational Journal of Pharmaceutics
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymersCyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymersJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administrationJournal of Controlled Release
Design and Pharmaceutical Applications of Prodrugs
Investigation of drug-cyclodextrin complexes by a phase-distribution methodChemical and Pharmaceutical Bulletin
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarbanJournal of Inclusion Phenomena
Cyclodextrins in drug deliveryExpert Opinion on Drug Delivery
Hydrolysis kinetics and QSAR investigation of soft antimicrobial agentsJournal of Pharmacy and Pharmacology
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: formation of aggregates and higher-order complexesInternational Journal of Pharmacy Practice
Cyclodextrins in drug delivery, Expert Opinion on Drug DeliveryAshley Publications

2004

Synthesis and Characterization of Chitosan N-betainates Having Various Degrees of SubstitutionMacromolecules
The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugsJournal of Drug Delivery Science and Technology
Applications of chemically-modified cyclodextrinsJournal of Drug Delivery Science and Technology
Marine lipids as building blocks for soft quaternary ammonium compounds and their antibacterial activityPharmazie
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugsPharmazie
Role of cyclodextrins in improving oral drug deliveryAmerican Journal of Drug Delivery
Self-Association of Cyclodextrins and Cyclodextrin ComplexesJournal of Pharmaceutical Sciences

2003

The effects of organic salts on the cyclodextrin solubilization of drugsInternational Journal of Pharmaceutics
Soft antimicrobial agentsJournal of Medicinal Chemistry
Sublingual delivery of 17β-estradiol from cyclodextrin containing tabletsPharmazie
Soft antibacterial agentsCurrent Medicinal Chemistry
The effects of cyclodextrins on topical delivery of hydrocortisoneS.T.P. Pharma Sciences
Investigation and physicochemical characterization of vinpocetine- sulfobutyl ether β-cyclodextrin binary and ternary complexesChemical and Pharmaceutical Bulletin
Examination of ¹⁹F-NMR as a tool for investigation of drug-cyelodextrin complexesDrug Development and Industrial Pharmacy

2002

Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigsInternational Journal of Pharmaceutics
The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systemsPharmazie
Cyclodextrins and the biopharmaceutics classification system of drugsJournal of Inclusion Phenomena
Cyclodextrins in eye drop formulationsJournal of Inclusion Phenomena
Self association and cyclodextrin solubilization of NSAIDsJournal of Inclusion Phenomena
Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexationInternational Journal of Pharmaceutics
Self-association and cyclodextrin solubilization of drugsJournal of Pharmaceutical Sciences
Cyclodextrins in eye drop formulationsActa Ophthalmologica Scandinavica
Fish skin as a model membrane to study transmembrane drug delivery with cyclodextrinsJournal of Inclusion Phenomena
The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranesJournal of Inclusion Phenomena
Cyclodextrins and drug permeability through semi-permeable cellophane membranesInternational Journal of Pharmaceutics
Cyclodextrins and drug permeability through semi-permeable cellophane membranesInternational Journal of Pharmaceutics
PrefaceJournal of Inclusion Phenomena
Cycloserine fatty acid derivatives as prodrugsChemical and Pharmaceutical Bulletin
Mucoadhesive sustained drug delivery system based on cationic polymer and anionic cyclodextrin/triclosan complexJournal of Inclusion Phenomena

2001

Intranasal administration of midazolam in a cyclodextrin based formulationPharmazie
Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complexPharmazie
Cyclodextrins in topical drug formulationsInternational Journal of Pharmaceutics
Cyclodextrin solubilization of benzodiazepinesInternational Journal of Pharmaceutics

2000

Dermal delivery of ETH-615, a zwitterionic drugDrug Development and Industrial Pharmacy
Marine lipids for prodrugs, soft compounds and other pharmaceutical applicationsPharmazie
Lipophilic metronidazole derivatives and their absorption through hairless mouse skinPharmazie
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertensionInvestigative Ophthalmology and Visual Science

1999

Methods to enhance the complexation efficiency of cyclodextrinsS.T.P. Pharma Sciences
Effect of cyclodextrins and polymers on triclosan availability and substantivity in toothpastes in vivoJournal of Pharmaceutical Sciences
Soft drugs based on hydrocortisone: The inactive metabolite approach and its application to steroidal antiinflammatory agentsPharmaceutical Research
Drug-cyclodextrin complexation in the presence of water-soluble polymersACS Symposium Series
Cyclodextrins as permeation enhancersJournal of Controlled Release
Diacyl glyceryl ester prodrugs for slow release in the skinPharmazie
Influence of cyclodextrins on the stability of the peptide salmon calcitonin in aqueous solutionInternational Journal of Pharmaceutics
Pharmaceutical applications of β-cyclodextrinPharmaceutical Technology
Pharmaceutical applications of β-CyclodextrinPharmaceutical Technology Europe
Synthesis of cyclic glycerol ether cyclodextrin derivatives and investigation of their binding properties with drugsJournal of Inclusion Phenomena

1998

Fatty acid extract from cod-liver oil: Activity against herpes simplex virus and enhancement of transdermal delivery of acyclovir in-vitroPharmacy and Pharmacology Communications
Stabilisation of ionic drugs through complexation with non-ionic and ionic cyclodextrinsInternational Journal of Pharmaceutics
Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrateDrug Development and Industrial Pharmacy
Cyclodextrins: new drug delivery systems in dermatologyInternational Journal of Dermatology
Cyclodextrin solubilization of ETH-615, a zwitterionic drugDrug Development and Industrial Pharmacy
Effect of the cod-liver oil extract on the buccal permeation of ionized and nonionized forms of ergotamine using the keratinized epithelial-free membrane of hamster cheek pouch mucosaInternational Journal of Pharmaceutics
Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrateProceedings of the Controlled Release Society
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage formsPharmaceutical Research
The effect of water-soluble polymers on the aqueous solubility and complexing abilities of β-cyclodextrinInternational Journal of Pharmaceutics
Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymersPharmazie
Aqueous hydrocortisone mouthwash solution: Clinical evaluationActa Odontologica Scandinavica
Cyclodextrins as co-enhancers in dermal and transdermal drug deliveryPharmazie

1997

Effect of various marine lipids on transdermal drug delivery - in vitro evaluationBollettino Chimico Farmaceutico
Cyclodextrin solubilization of water-soluble drugs: Calcipotriol and EB-1089Pharmazie
Effect of cyclodextrins on topical drug delivery to the eyeDrug Development and Industrial Pharmacy
Unsaturated glycerol monoethers as novel skin penetration enhancersPharmazie
Formulation and testing of methazolamide cyclodextrin eye drop solutionsJournal of Controlled Release

1996

Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrinJournal of Controlled Release
The effect of water-soluble polymers on aqueous solubility of drugsInternational Journal of Pharmaceutics
Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and StabilizationJournal of Pharmaceutical Sciences
Effects of cyclodextrins and polymers on transdermal drug deliveryProceedings of the Controlled Release Society
Formulation and clinical evaluation of a hydrocortisone solution for the treatment of oral diseaseInternational Journal of Pharmaceutics
Design and in vivo testing of 17β-estradiol-HPβCD sublingual tabletsPharmazie
The influence of water-soluble polymers and pH on hydroxypropyl-β-cyclodextrin complexation of drugsDrug Development and Industrial Pharmacy
Complexation of Drug Compounds with Ionic and Non-Ionic Cyclodextrins
Effects of cyclodextrins and polymers on topical drug delivery to the eye - Evaluations in humansProceedings of the Controlled Release Society
Dexamethasone-cyclodextrin-polymer co-complexes in aqueous eye dropsInvestigative Ophthalmology and Visual Science
Topically effective acetazolamide eye-drop solution in manPharmaceutical Sciences

1995

Fatty acids from cod-liver oil as skin penetration enhancersPharmazie
Formulation development for a zidovudine chemical delivery system 1. Parenteral dosage formsInternational Journal of Pharmaceutics
Improved acitretin delivery through hairless mouse skin by cyclodextrin complexationInternational Journal of Pharmaceutics
Formulation development for a zidovudine chemical delivery system 2. Towards oral and non-parenteral dosage formsInternational Journal of Pharmaceutics
The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skinInternational Journal of Pharmaceutics
Preparation, characterization, and anesthetic properties of 2- hydroxypropyl-β-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouseJournal of Pharmaceutical Sciences

1994

The pharmacokinetics and transdermal delivery of loteprednol etabonate and related soft steroidsAdvanced Drug Delivery Reviews
Effect of cyclodextrins on the degradation of cortisone acetate, oestradiol benzoate and prednicarbate in aqueous solutionS.T.P. Pharma Sciences
The effect of water-soluble polymers on drug-cyclodextrin complexationInternational Journal of Pharmaceutics
The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on HPβCD complexation of hydrocortisone and its permeability through hairless mouse skinEuropean Journal of Pharmaceutical Sciences
The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulationsInternational Journal of Pharmaceutics
The influence of cyclodextrins on the stability of cephalotin and aztreonam in aqueous solutionsPharmazie
2-hydroxypropyl-β-cyclodextrin in topical carbonic anhydrase inhibitor formulationsEuropean Journal of Pharmaceutical Sciences
The influence of 2-hydroxypropyl-β-cyclodextrin on diffusion rates and transdermal delivery of hydrocortisoneDrug Development and Industrial Pharmacy
Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbitsJournal of Pharmacy and Pharmacology
Pharmacy in icelandAnnals of Pharmacotherapy

1993

Topical delivery of acetazolamide for psoriasisActa Dermato-Venereologica
Cyclodextrin complexation of NSAIDs: Physicochemical characteristicsEuropean Journal of Pharmaceutical Sciences
The effect of cyclodextrins on the solubility and stability of medroxyprogesterone acetate and megestrol acetate in aqueous solutionInternational Journal of Pharmaceutics
Nýjar aðferðir til að hafa áhrif á frásog og dreifingu lyfjaLæknablaðið

1992

Interactions between preservatives and 2-hydroxypropyl-β-cyclodextrinDrug Development and Industrial Pharmacy
Stabilizing Effect of Tris(hydroxymethyl)aminomethane on N-Nitrosoureas in Aqueous SolutionsJournal of Pharmaceutical Sciences
Preparation and physical evaluation of microcapsules of hydrophilic drug-cyclodextrin complexesJournal of Microencapsulation
Degradation of tauromustine (TCNU) in aqueous solutionsActa Pharmaceutica Nordica
Effect of various cyclodextrins on solution stability and dissolution rate of doxorubicin hydrochlorideInternational Journal of Pharmaceutics
The stability of aspartame in aqueous solutionsActa Pharmaceutica Nordica
Estramustine: Hydrolysis, solubilization, and stabilization in aqueous solutionsInternational Journal of Pharmaceutics
Metabolism, Distribution, and Transdermal Permeation of a Soft Corticosteroid, Loteprednol EtabonatePharmaceutical Research
Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systemsPharmaceutical Research

1991

Solubilization and stabilization of a benzylpenicillin chemical delivery system by 2-hydroxypropyl-β-cyclodextrinPharmaceutical Research
Solubilization and stabilization of drugs through cyclodextrin complexationActa Pharmaceutica Nordica
Stabilization of aspartame by cyclodextrinsInternational Journal of Pharmaceutics
The effects of cyclodextrins on transdermal delivery of drugsEuropean Journal of Pharmaceutics and Biopharmaceutics
Cyclodextrin-accelerated degradation of β-lactam antibiotics in aqueous solutionsInternational Journal of Pharmaceutics
2-Hydroxypropyl-β-cyclodextrin: Properties and usage in pharmaceutical formulationsPZ Wissenschaft

1990

The effect of 2-hydroxypropyl-β-cyclodextrin on the simultaneous dissolution and degradation of chlorambucilInternational Journal of Pharmaceutics
Comparative study on inclusion complexation of acetylsalicylic acid, cholecalciferol and melphalan with β- and γ-cyclodextrin and some of their derivativesActa Pharmaceutica Nordica
Degradation of lomustine (CCNU) in aqueous solutionsInternational Journal of Pharmaceutics
Novel central nervous system targeted semisynthetic penicillinsDrug Design and Delivery
The effect of phosphine oxides on transdermal deliveryActa Pharmaceutica Nordica

1989

The effects of 2-hydroxypropyl-β-cyclodextrin on the solubility and stability of chlorambucil and melphalan in aqueous solutionInternational Journal of Pharmaceutics
Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiolActa Pharmaceutica Nordica
Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairles mouse skin in vitroActa Pharmaceutica Nordica
Effect of oleic acid on diffusion of drugs through hairless mouse skinActa Pharmaceutica Nordica

1988

Improved delivery through biological membranes XXXI: Solubilization and stabilization of an estradiol chemical delivery system by modified β-cyclodextrinsJournal of Pharmaceutical Sciences

1987

The effect of vehicle additives on the transdermal delivery of nitroglycerinPharmaceutical Research
Trifluorothymidine: potential non-invasive diagnosis of herpes simplex infection using 19F nuclear magnetic resonance in a murine hepatitis modelJournal of Virological Methods

1985

The effect of ionization on partition coefficients and topical deliveryActa Pharmaceutica Suecica

1984

Synthesis and evaluation of novel lidocaine sulfur analogsInternational Journal of Pharmaceutics
Soft drugs VI. The application of the inactive metabolite approach for design of soft β-blockersPharmaceutical Research

1981

Improved delivery through biological membranes X: Percutaneous absorption and metabolism of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugsJournal of Pharmaceutical Sciences
Improved delivery through biological membranes IX: Kinetics and mechanism of hydrolysis of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugsJournal of Pharmaceutical Sciences
Improved delivery through biological membranes VIII: Design, synthesis, and in vivo testing of true prodrugs of aspirinJournal of Pharmaceutical Sciences

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