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Gunnar Guðmundsson - Prófessor

Gunnar Guðmundsson

–

Heilbrigðisvísindasvið

Gunnar Guðmundsson

Prófessor

Lyflækningar-öndunarfærasjúkdómar

Aðsetur
LSH - Fossvogi
Sími
5436876
Tölvupóstur
ggudmund [hjá] hi.is

Starfseining
Læknadeild
Vefsíða
http://www.landspitali.is

ORCID vefsíða
https://orcid.org/0000-0002-7251-8322
Rannsóknagátt – Gunnar Guðmundsson

Útgefið efni

2024

Surgical lung biopsy for suspected interstitial lung disease with video-assisted thoracoscopic surgery is safe, providing exact histological and disease specific diagnosis for tailoring treatmentJournal of Thoracic Disease
Global mortality and readmission rates following COPD exacerbation-related hospitalization: a meta-analysis of 65945 individual patientsERJ Open Research

2023

PRS-ing Forward to Identify Genetic Risk in Idiopathic Pulmonary FibrosisAmerican journal of respiratory and critical care medicine
Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare VariantsAmerican journal of respiratory and critical care medicine
Letter from IcelandRespirology
Proteomic associations with forced expiratory volumeRespiratory Research
Letter from IcelandRespirology
Cohort ProfileInternational Journal of Epidemiology
Ambient air pollution and emergency department visits and hospitalisation for cardiac arrestBMJ Open

2022

Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung AbnormalitiesAmerican Journal of Respiratory and Critical Care Medicine
Detection and Early Referral of Patients With Interstitial Lung AbnormalitiesChest
Ethical dilemmas in physicians’ consultations with COPD patientsInternational Journal of COPD
Interstitial lung abnormalities are associated with decreased mean telomere lengthThe European respiratory journal
The relationship between interstitial lung abnormalities, mortality, and multimorbidityThorax
Respiratory function and CT abnormalities among survivors of COVID-19 pneumoniaBMJ Open Respiratory Research
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillationEnvironmental Health: A Global Access Science Source
The Proteomic Profile of Interstitial Lung AbnormalitiesAmerican Journal of Respiratory and Critical Care Medicine
Obstructive sleep apnea is an independent risk factor for severe COVID-19Sleep

2021

Overlap of genetic risk between interstitial lung abnormalities and idiopathic pulmonary fibrosisAmerican Journal of Respiratory and Critical Care Medicine
Illness severity and risk of mental morbidities among patients recovering from COVID-19BMJ Open
Eldgos og eitraðar lofttegundirLæknablaðið
Breytingar í lungnavef á tölvusneiðmyndum sjúklinga með kórónuveirusjúkdóm 2019 (COVID-19)Læknablaðið
Chronic airflow obstruction and ambient particulate air pollutionThorax
Mat á lungnastarfsemi fyrir skurðaðgerðir.Læknaneminn
Óráð og hiti: sjaldgæf en hættuleg orsök - SjúkratilfelliLæknablaðið
Eldgos og eitraðar lofttegundirLæknablaðið
Interstitial lung abnormalities–current knowledge and future directionsEuropean Clinical Respiratory Journal
Progression of traction bronchiectasis/bronchiolectasis in interstitial lung abnormalities is associated with increased all-cause mortalityEuropean Journal of Radiology Open
Óráð og hiti – sjaldgæf en hættuleg orsök.Læknablaðið
Breytingar í lungnavef á tölvusneiðmyndum sjúklinga með kórónuveirusjúkdóm 2019 (COVID-19)Læknablaðið
Associations of ω-3 Fatty Acids with Interstitial Lung Disease and Lung Imaging Abnormalities among AdultsAmerican Journal of Epidemiology

2020

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary FibrosisAmerican Journal of Respiratory and Critical Care Medicine
Áhrif lungnasjúkdóma, reykinga og rafrettunotkunar á alvarleika einkenna við greiningu COVID-19Læknablaðið
Berkjuskúlk - YfirlitLæknablaðið
The impact of lung diseases, smoking and e-cigarette use on the severity of COVID-19 illness at diagnosisLæknablaðið
Traction Bronchiectasis/Bronchiolectasis is Associated with Interstitial Lung Abnormality MortalityEuropean Journal of Radiology
Frustrated caringInternational Journal of Chronic Obstructive Pulmonary Disease
The associations of interstitial lung abnormalities with cancer diagnoses and mortalityThe European respiratory journal
Bronchiectasis - a reviewLæknablaðið
Hæðarveiki og tengdir sjúkdómarLæknablaðið
Hiatus hernia and interstitial lung abnormalitiesEuropean Respiratory Journal
Áhrif lungnasjúkdóma, reykinga og rafrettunotkunar á alvarleika einkenna við greiningu COVID-19Læknablaðið
Associations of Omega-3 Fatty acids with Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults.American Journal of Epidemiology

2019

Oxygen in patients with fibrotic interstitial lung disease: an international Delphi surveyThe European respiratory journal
Effects of cardiac rehabilitation on the physical capacity of individuals with heart failureLæknablaðið
Resequencing study confirms that host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosisAmerican Journal of Respiratory and Critical Care Medicine
Imaging patterns are associated with interstitial lung abnormality progression and mortalityAmerican Journal of Respiratory and Critical Care Medicine
High altitude illness and related diseases - a reviewLæknablaðið
Asbestos and its effects on health of Icelanders - reviewLæknablaðið
Air pollution in Iceland and the effects on human health. ReviewLæknablaðið
A MUC5B polymorphism associated with Idiopathic Pulmonary Fibrosis mediates overexpression through decreased CpG methylation and C/EBPβ transcriptional activation
Asbest og áhrif þess á heilsufar Íslendinga - YfirlitsgreinLæknablaðið
Diagnostic imaging in adult non-cystic fibrosis bronchiectasisBreathe
Loftmengun á Íslandi og áhrif hennar á heilsu manna - YfirlitsgreinLæknablaðið
Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilunLæknablaðið
Hæðarveiki og tengdir sjúkdómarLæknablaðið
Loftmengun á Íslandi og áhrif hennar á heilsu manna - YfirlitsgreinLæknablaðið
Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilunLæknablaðið
COPD patients’ experiences, self-reported needs, and needs-driven strategies to cope with self-managementInternational Journal of Chronic Obstructive Pulmonary Disease
Seismicity of the Hengill area, SW IcelandJournal of Volcanology and Geothermal Research

2018

Analysis of pulmonary features and treatment approaches in the COPA syndromeERJ Open Research
Interstitial lung abnormalities and physical functionERJ Open Research
Mengun af völdum flugelda og áhrif á lungnaheilsu ÍslendingaLaeknabladid
Interstitial lung abnormalities and self-reported health and functional statusThorax

2017

COPA syndrome in an Icelandic family caused by a recurrent missense mutation in COPABMC Medical Genetics
Efling heilbrigðis og sjálfsumönnunar hjá fólki með væga og miðlungsalvarlega langvinna lungnateppu - Hagnýting niðurstaðna.Tímarit hjúkrunarfræðinga
COPA syndrome in an Icelandic family caused by a recurrent missense mutation in COPABMC Medical Genetics
Treatment of idiopathic pulmonary fibrosisJournal of Internal Medicine
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypesEuropean Respiratory Journal

2016

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumoniaBMC Genetics
Association between interstitial lung abnormalities and all-cause mortalityJAMA - Journal of the American Medical Association
Áhrif eldgosa á heilsu manna á Íslandi YfirlitsgreinLaeknabladid
Malignant mesothelioma incidence by nation-wide cancer registryJournal of Occupational Medicine and Toxicology
Áhrif eldgosa á heilsu manna á Íslandi. YfirlitsgreinLæknablaðið
Lungnaígræðslur á ÍslendingumLæknablaðið
Airflow obstruction, atherosclerosis and cardiovascular risk factors in the AGES Reykjavik studyAtherosclerosis
Lungnaígrslur á ÍslendingumLaeknabladid

2015

Effectiveness of a partnership-based self-management programme for patients with mild and moderate chronic obstructive pulmonary diseaseJournal of Advanced Nursing
Organisation of diagnosis and treatment of idiopathic pulmonary fibrosis and other interstitial lung diseases in the Nordic countriesEuropean Clinical Respiratory Journal
Brád versnun á langvinnri lungnateppu YfirlitsgreinLaeknabladid
Evidence for Proinflammatory β-1,6 Glucans in the Pneumocystis carinii Cell Wall.Infection and Immunity
Áhrif hjartaendurhæfingar HL-stöðvarinnar eftir kransæðahjáveituaðgerð eða annað kransæðainngripLæknablaðið
Bráð versnun á langvinnri lungnateppu - yfirlitsgreinLæknablaðið
Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in cultureLaboratory Investigation

2014

Eru tengsl á milli innúdastera og lungnabólgu?Laeknabladid

2013

Lugnarek: sigrar og framtíðarvon.Læknablaðið
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosisNature Genetics
ErratumNature Genetics
Prevalence of airflow obstruction in nonsmoking older individuals using different spirometric criteriaCOPD: Journal of Chronic Obstructive Pulmonary Disease
LungnarekLaeknabladid
Sjúkratilfelli: öndunarfæraeinkenni hjá sundmanni.Læknablaðið
Effects of Eyjafjallajökull volcanic ash on innate immune system responses and bacterial growth in vitroEnvironmental Health Perspectives

2012

Algengi reykinga og langvinnrar lungnateppu hjá skjólstæðingum Heilsugæslustöðvarinnar á AkureyriLæknablaðið
Long-term survival in patients hospitalized for chronic obstructive pulmonary diseaseInternational Journal of COPD
Middle lobe syndromeRespiration
Algengi reykinga og langvinnrar lungnateppu hjá skjólstæðingum Heilsugæslustöðvarinnar á AkureyriLæknablaðið
Hot off the breathThorax
Greining, meðferð og horfur lungnabólguLæknabladid

2011

A common MUC5B promoter polymorphism and pulmonary fibrosisNew England Journal of Medicine
COPD in never smokersChest
Smoking, stages of change and decisional balance in Iceland and SwedenClinical Respiratory Journal
Sameinuðu þjóðirnar og ósmitnæmir sjúkdómarLaeknabladid
Respiratory health effects of volcanic ash with special reference to Iceland. A reviewClinical Respiratory Journal

2010

Miðmætisspeglanir á ÍslandiLæknablaðið
Buist, and for the BOLD Collaborative Research Group. COPD in Never-Smokers: Results from the population-based BOLD Study.Chest
Miomætisspeglanir á íslandiLaeknabladid
Fárveikir sjúklingar með inflúensu A (H1N1)v 2009 og skjót birting greina hjá Læknablaðinu [ritstjórnargrein]Læknablaðið

2009

Geðheilsa og líðan íslenskra bændaLæknablaðið
Chronic airflow obstruction and markers of systemic inflammationRespiratory Medicine
Hypertension, systemic inflammation and body weight in relation to lung function impairmentan epidemiological studyCOPD: Journal of Chronic Obstructive Pulmonary Disease
Diagnostic Surgical Lung Biopsies for Suspected Interstitial Lung DiseasesAnnals of Thoracic Surgery
Sjálfsprottid loftmiðmæti eftir iðkun jógaLaeknabladid
Almennt heilsufar íslenskra bændaLaeknabladid
Vinnuslys íslenskra bænda : mat á áhættuþáttum með spurningalistaLæknablaðið
Middle lobe syndromeClinical Respiratory Journal
Hæðarveiki, yfirlitsgreinLæknablaðið

2008

Trefjavefslungnabólga : yfirlitsgreinLæknablaðið
Respiratory disorders are not more common in farmers. Results from a study on Icelandic animal farmersRespiratory Medicine
Seismic and geodetic insights into magma accumulation at Katla subglacial volcano, IcelandJournal of Geophysical Research: Solid Earth
Syfja og aksturLaeknabladid
Fyrirferð í brjóstholi -ekki er allt sem sýnist?Læknablaðið
Maurar í húsryki á íslenskum bóndabæjumLæknablaðið

2007

Ekki er allt astmi sem hvæsir : sjúkratilfelliLæknablaðið
Nutritional status and long-term mortality in hospitalised patients with chronic obstructive pulmonary disease (COPD)Respiratory Medicine
Langvinn eósínófíl lungnabólga á Íslandi. Faraldsfræði, klínísk einkenni og yfirlitLæknablaðið
Langvinn eósínófíl lungnabólga á Islandi Faraldsfraedi, klínísk einkenni og yfirlit.Læknabladid
Hversu algeng er langvinn lungnateppa? Íslensk faraldsfræðirannsóknLæknabladid
Clinical features in secondary and cryptogenic organising pneumoniaInternational Journal of Tuberculosis and Lung Disease

2006

Trefjavefslungnabólga tengd notkun lyfsins amíódarón : sjúkratilfelli og yfirlitLæknablaðið
Mortality in COPD patients discharged from hospitalRespiratory Research
Interstitial and infiltrative pulmonary disorders.
Depression, anxiety and health status after hospitalisation for COPDRespiratory Medicine
Characteristics of hospitalised patients with COPD in the Nordic countriesRespiratory Medicine
Epidemiology of organising pneumonia in IcelandThorax

2005

Klínískar leidbeiningar Landspítala um greiningru og medferd brádaversnunar á astma.Læknabladid
Risk factors for rehospitalisation in COPDEuropean Respiratory Journal
Forecasting and monitoring a subglacial eruption in IcelandEos
Öndunarmælingar í heilsugæslu : tækifæri og takmarkanir [ritstjórnagrein]Læknablaðið
Lungnaástungur med hjálp tölvusneidmynda á Landspítala. Abendingar, fylgikvillar og útkoma.Læknabladid
Hálmsótt eda heysótt?Læknabladid

2004

Öndunarmælingar á heilsugæslustöð : ábendingar, niðurstöður og gæðiLæknablaðið
Meðferð með ytri öndunarvél við bráðri öndunarbilunLæknablaðið

2003

Rehospitalizations for chronic obstructive pulmonary disease: risk factors and possible interventions. Lung Forum
Lungnaslagæðaháþrýstingur : nýjungar í meðferð og sjúkratilfelliLæknablaðið
Lokuð fleiðrusýnataka með nál á Íslandi árin 1990-1999Læknablaðið
Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to EndotoxinJournal of Biological Chemistry

2002

Interstitial and infiltrative pulmonary disorders.
Greining atvinnusjúkdóma : dæmi úr kúfiskvinnsluLæknablaðið

2001

The cerebral hemorrhage-producing cystatin C variant (L68Q) in extracellular fluidsAmyloid
Hlutverk innúðastera í meðferð langvinnra lungnateppusjúkdóma er að skýrast [ritstjórnargrein]Læknablaðið
Íslenskir sjúklingar með öndunarvél heima : nýr meðferðarmöguleikiLæknablaðið

2000

Detailed distribution of microearthquakes along the northern Reykjanes Ridge, off SW-IcelandGeophysical Research Letters
LungnaígræðslaLæknablaðið
Crustal structure of central and northern Iceland from analysis of teleseismic receiver functionsGeophysical Journal International
Lungnasjúkdómar

1999

A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophagesJournal of Immunology
Viral infection modulates expression of hypersensitivity pneumonitisJournal of Immunology
Shotcrete applications and minimising the risk of damaging alkali- aggregate reaction in rock support for a subsea, geothermally active environment - Hvalfjordur Tunnel, Iceland
Respiratory epithelial cells release IL-8 in response to thermophilic bacteria causing hypersensitivity pneumonitis.Experimental Lung Research
Sarcoidosis
Respiratory epithelial cells release interleukin-8 in response to a thermophilic bacteria that causes hypersensitivity pneumonitisExperimental Lung Research

1998

Changes in PKC isoforms in human alveolar macrophages compared with blood monocytesAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
Interleukin-10 modulates severity of inflammatory response in Hypersensitivity Pneumonitis.American Journal of Respiratory Cell and Molecular Biology
Changes in PKC isoforms and phorbol ester-induced mitogen activated protein kinase activity in human alveolar macrophages compared to blood monocytes.American Journal of Physiology - Lung Cellular and Molecular Physiology
Interleukin-10 modulates the severity of hypersensitivity pneumonitis in miceAmerican Journal of Respiratory Cell and Molecular Biology
IL-12 modulates expression of hypersensitivity pneumonitisJournal of Immunology

1997

Spirometric values in obese individualsAmerican Journal of Respiratory and Critical Care Medicine
Interferon-γ is necessary for the expression of hypersensitivity pneumonitisJournal of Clinical Investigation
Interferon-γ ist notwendig für die ausbildung einer exogen-allergischen alveolitisPneumologie
Pathophysiology of hospital-acquired pneumoniaSeminars in Respiratory and Critical Care Medicine

1996

Middle lobe syndromeAmerican Family Physician
Human cystatin C expression and regulation by TGF-β1Amyloid
Progressive dementia and leucoencephalopathy as the initial presentation of late onset hereditary cystatin-C amyloidosis. Clinicopathological presentation of two casesJournal of the Neurological Sciences

1994

Predisposition to cytomegalovirus infection of the gastrointestinal tract [1]Annals of Internal Medicine

1992

Fleiðruholsvökvi : rannsókn á níutíu og sex sjúklingum á BorgarspítalaLæknablaðið

1989

Arfgeng heilablæðing I : vitglöp við cystatin C mýlildiLæknablaðið
Arfgeng heilablæðing II : útfellingar sýstatín-C mýlildisefnis í húðLæknablaðið

Sérsvið:

Lungnasjúkdómar

Langvinn lungnateppa