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Samgöngur
Vilmundur G Guðnason - Professor Emeritus
–
School of Health Sciences
Vilmundur G Guðnason
Íslenska
Professor Emeritus
Location
Utan H.Í.
Phone
5351800
Email
vgg [at] hi.is
Unit
Faculty of Medicine
Website
https://scholar.google.com/citations?user=eDkARCwAAAAJ;
ORCID site
https://orcid.org/0000-0001-5696-0084
Research portal – Vilmundur G Guðnason
Published works
2026
A meta-analysis of smoking and fracture risk to update the FRAX® tool
Osteoporosis International
FSH and longitudinal changes in bone marrow adipose tissue composition in older adults
Bone
The association between cerebral “dirty-appearing” white matter and progression of small vessel disease in community-dwelling older adults
Journal of Cerebral Blood Flow and Metabolism
Large-scale blood pressure GWAS accounting for gene-depression interactions in 564,680 individuals from diverse populations
Human Genetics and Genomics Advances
Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older Adults
Circulation. Genomic and precision medicine
Midlife and late-life population attributable fractions of risk factors for dementia in the United States
Alzheimer's and Dementia
2025
Public Health
Alzheimer's & dementia : the journal of the Alzheimer's Association
Automated interstitial lung abnormalities detection at CT
Japanese Journal of Radiology
Socioeconomic Status and Associations with Nutrition in Icelandic Community-Dwelling Older Adults
Nutrients
Circulating causal protein networks linked to future risk of myocardial infarction
Nature Communications
The clinical utility of imaging in osteoarthritis and its importance in future prediction of total hip replacement; a nested case-control study within the AGES-Reykjavik cohort
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Cardiac Troponins and Cardiovascular Disease Risk Prediction
Journal of the American College of Cardiology
Clinical and Imaging Markers of Cardiac Function and Brain Health A Meta-Analysis of Community-Based Studies
Neurology
Long-Term Feasibility and Outcomes of a Digital Health Program to Improve Liver Fat and Cardiometabolic Markers in Individuals With Nonalcoholic Fatty Liver Disease
JMIR Cardio
Social Support/Network and Depressive Symptoms Among Community- Dwelling Older Adults During 5 Years of Follow-Up
Clinical Gerontologist
Polygenic prediction of body mass index and obesity through the life course and across ancestries
Nature Medicine
Birth size modifies longitudinal associations between midlife educational level and physical function at late-life for men and women
BMC Geriatrics
Family history of fracture and fracture risk
Osteoporosis International
Rheumatoid arthritis and subsequent fracture risk
Osteoporosis International
A more irregular shape of white matter hyperintensities is associated with cognitive decline over five years in community-dwelling older adults
Neurobiology of Aging
Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease
Nature Communications
Basic Science and Pathogenesis
Alzheimer's & dementia : the journal of the Alzheimer's Association
KI zur automatisierten vBMD- und Fragilitätsanalyse des proximalen Femurs an CT-Scans
Osteologie
Long-term temporal stability of circulating proteins in older adults
bioRxiv : the preprint server for biology
Impact of Balance and Dizziness Problems on Falls in Older Adults
Laryngoscope investigative otolaryngology
Mid- and late-life cardiovascular health indicators and changes in biological ageing Markers; A multi-cohort study
EBioMedicine
Sex differences in allostatic load profiles and incident dementia
Journal of Alzheimer's Disease
Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults
Journal of the American Heart Association
Associations of albuminuria with interstitial lung abnormalities in older community-dwelling adults confounded by age
ERJ Open Research
A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations
Molecular Psychiatry
Sex Differences in Progression of Neurodegeneration
Neurodegenerative Diseases
Body mass index and subsequent fracture risk
Journal of Bone and Mineral Research
Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids
Translational Psychiatry
Systematic comparison of observational and Mendelian Randomization estimates for cardiometabolic proteomic signatures
medRxiv : the preprint server for health sciences
Higher FSH Level Is Associated with Increased Risk of Incident Hip Fracture in Older Adults, Independent of Sex Hormones
Journal of Clinical Endocrinology and Metabolism
Trabecular texture and paraspinal muscle characteristics for prediction of first vertebral fracture
Frontiers in Endocrinology
2024
A genome-wide association meta-analysis of all-cause and vascular dementia
Alzheimer's and Dementia
Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia
Neurology
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022
The Lancet
Worldwide trends in underweight and obesity from 1990 to 2022
The Lancet
Correction to
Nature Genetics
Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality
Nature Communications
White matter hyperintensity shape is related to long-term progression of cerebrovascular disease in community-dwelling older adults
Journal of Cerebral Blood Flow and Metabolism
User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease
JMIR Cardio
SMIM1 absence is associated with reduced energy expenditure and excess weight
Med
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Nature Genetics
Refracture and mortality risk in the elderly with osteoporotic fractures
Osteoporosis International
The magnitude and direction of the relationship between risk factor and cognition depends on age
European Journal of Epidemiology
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s disease
Nature Aging
Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach
Hypertension
Omega-3 Blood Levels and Stroke Risk
Stroke
Proteomic analysis of Alzheimer’s disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment
Science Translational Medicine
A meta-analysis of previous falls and subsequent fracture risk in cohort studies
Osteoporosis International
A new hip fracture risk index derived from FEA-computed proximal femur fracture loads and energies-to-failure
Osteoporosis International
Genetic variants for head size share genes and pathways with cancer
Cell Reports Medicine
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Nature Genetics
Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia
JAMA network open
Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance
Alzheimer's Research and Therapy
Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure
Kidney International Reports
Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older Adults
Neurology
Depression and Dementia
Advances in Alzheimer's Disease
Cohort Profile
International Journal of Epidemiology
Correction to
Nature Aging
Male-female spatio-temporal differences of age-related bone changes show faster bone deterioration in older women at femoral regions associated with incident hip fracture
Journal of Bone and Mineral Research
Depressive symptoms score predicts incident type 2 diabetes in community dwelling old Icelandic people
Journal of Gerontology and Geriatrics
Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease
Circulation
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nature Genetics
Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker
Alzheimer's and Dementia
Panel estimated Glomerular Filtration Rate (GFR)
PLoS ONE
Peripheral risk factors and their role in biomarker-based screening for dementia in the community
Alzheimer's and Dementia
2023
Genetic Risk Score for Intracranial Aneurysms
Stroke
Dementia prediction in the general population using clinically accessible variables
BMC Medical Informatics and Decision Making
Identification of circulating proteins associated with general cognitive function among middle-aged and older adults
Communications Biology
Milk intake and hip fracture incidence in community-dwelling old Icelandic adults
Osteoporosis International
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
Frontiers in Genetics
Comparative study of machine learning methods for modeling associations between risk factors and future dementia cases
GeroScience
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization
Wellcome Open Research
Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia
GeroScience
Diminishing benefits of urban living for children and adolescents’ growth and development
Nature
White matter hyperintensity shape is associated with long-term dementia risk
Alzheimer's and Dementia
A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Identification of biomarkers for glycaemic deterioration in type 2 diabetes
Nature Communications
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
Nature Genetics
Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries
The Lancet Diabetes and Endocrinology
Proteomic Analysis Identifies Circulating Proteins Associated With Plasma Amyloid-β and Incident Dementia
Biological Psychiatry Global Open Science
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
Nature
Late-life depression, allostatic load, and risk of dementia
Psychoneuroendocrinology
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis
European Heart Journal
Discordance Between Creatinine-Based and Cystatin C–Based Estimated GFR
Kidney Medicine
Proteomic prediction of incident heart failure and its main subtypes
European Journal of Heart Failure
CKD-EPI and EKFC GFR Estimating Equations
Journal of the American Society of Nephrology : JASN
Previous fracture and subsequent fracture risk
Osteoporosis International
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease
Nature Genetics
2022
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
Diabetes Care
Circulating serum microRNAs including senescent miR-31-5p are associated with incident fragility fractures in older postmenopausal women with type 2 diabetes mellitus
Bone
Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population
Nature Communications
APOE epsilon 4 and late-life cognition: mediation by structural brain imaging markers
European Journal of Epidemiology
Carotid plaque is strongly associated with coronary artery calcium and predicts incident coronary heart disease in a population-based cohort
Atherosclerosis
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning
Molecular Psychiatry
Cerebrovascular Risk-Factors of Prevalent and Incident Brain Infarcts in the General Population
Stroke
Social network and the risk for developing mild cognitive impairment and dementia among older adults
Aging clinical and experimental research
Áhrif menntunar á áhættuþætti og nýgengi æðakölkunarsjúkdóma
Læknablaðið
Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung Abnormalities
American Journal of Respiratory and Critical Care Medicine
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
American Journal of Human Genetics
A joint ventricle and WMH segmentation from MRI for evaluation of healthy and pathological changes in the aging brain
PLoS ONE
A population-based meta-analysis of circulating GFAP for cognition and dementia risk
Annals of Clinical and Translational Neurology
Correction
American Journal of Clinical Nutrition
Interstitial lung abnormalities are associated with decreased mean telomere length
The European respiratory journal
Association of change in cardiovascular risk factors with incident dementia
Alzheimer's and Dementia
Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures
Osteoporosis International
A genome-wide association study of serum proteins reveals shared loci with common diseases
Nature Communications
Saturated and Unsaturated Bone Marrow Lipids Have Distinct Effects on Bone Density and Fracture Risk in Older Adults
Journal of Bone and Mineral Research
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Genome Biology
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Nature Genetics
Finite element derived femoral strength is a better predictor of hip fracture risk than aBMD in the AGES Reykjavik study cohort
Bone
Erratum
Nature
Stroke genetics informs drug discovery and risk prediction across ancestries
Nature
Update of the fracture risk prediction tool FRAX
Osteoporosis International
Associations of Pulmonary Function with MRI Brain Volumes
Journal of Alzheimer's disease : JAD
A proteogenomic signature of age-related macular degeneration in blood
Nature Communications
Fast and robust femur segmentation from computed tomography images for patient-specific hip fracture risk screening
Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate
Brain
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss
American Journal of Human Genetics
Correction: Association of low-frequency and rare coding variants with information processing speed
Translational Psychiatry
Creativity, leisure activities, social engagement and cognitive impairment
Aging clinical and experimental research
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Nature Genetics
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Nature Genetics
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
Journal of Thrombosis and Haemostasis
A saturated map of common genetic variants associated with human height
Nature
Growth Rate in Childhood and Adolescence and the Risk of Breast and Prostate Cancer
American Journal of Epidemiology
Depressive symptom profiles predict dementia onset and brain pathology in older persons. The AGES-Reykjavik study
Neurobiology of Aging
The Proteomic Profile of Interstitial Lung Abnormalities
American Journal of Respiratory and Critical Care Medicine
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals
Communications Biology
Coding and regulatory variants are associated with serum protein levels and disease
Nature Communications
Mid- and later-life risk factors for predicting neuropathological brain changes associated with Alzheimer's and vascular dementia: The Honolulu Asia Aging Study and the Age, Gene/Environment Susceptibility-Reykjavik Study
Alzheimer's & dementia : the journal of the Alzheimer's Association
The relationship between interstitial lung abnormalities, mortality, and multimorbidity
Thorax
PUFA ω-3 and ω-6 biomarkers and sleep
American Journal of Clinical Nutrition
Depression and Dementia
Journal of Alzheimer's Disease
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease
Circulation
Cognition and brain health among older adults in Iceland
GeroScience
2021
A poor appetite or ability to eat and its association with physical function amongst community-dwelling older adults
European Journal of Ageing
Exploratory assessment of pineal gland volume, composition, and urinary 6-sulfatoxymelatonin levels on prostate cancer risk
Prostate
Serum 25-Hydroxy-Vitamin D Status and Incident Hip Fractures in Elderly Adults
Journal of Bone and Mineral Research
Dietary patterns in adolescence and risk of colorectal cancer
Cancer Causes and Control
Overlap of genetic risk between interstitial lung abnormalities and idiopathic pulmonary fibrosis
American Journal of Respiratory and Critical Care Medicine
New creatinine- And cystatin C-based equations to estimate GFR without race
New England Journal of Medicine
Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Human Molecular Genetics
Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk
Nature Aging
Progression of traction bronchiectasis/bronchiolectasis in interstitial lung abnormalities is associated with increased all-cause mortality
European Journal of Radiology Open
Wave reflection at the origin of a first-generation branch artery and target organ protection
Hypertension
Genetic insights into biological mechanisms governing human ovarian ageing
Nature
Publisher Correction
Nature Communications
Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes
Circulation: Genomic and Precision Medicine
Diffuse idiopathic skeletal hyperostosis in elderly Icelanders and its association with the metabolic syndrome
Scandinavian Journal of Rheumatology
Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location
Osteoporosis International
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction
Human Molecular Genetics
Publisher Correction
Nature Genetics
Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study
Osteoporosis International
The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture
Osteoporosis International
Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations with Atrial Fibrillation
Circulation: Genomic and Precision Medicine
Accelerated decline in quadriceps area and Timed Up and Go test performance are associated with hip fracture risk in older adults with impaired kidney function
Experimental Gerontology
rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD
Journal of Hepatology
The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture
Osteoporosis International
Serum levels of ACE2 are higher in patients with obesity and diabetes
Obesity Science and Practice
It's in Our Blood
Trends in Molecular Medicine
Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018
Læknablaðið
Soft tissue radiodensity parameters mediate the relationship between self-reported physical activity and lower extremity function in AGES-Reykjavík participants
Scientific Reports
A Noncoding Variant near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects against Myocardial Infarction
Journal of Clinical Endocrinology and Metabolism
Copeptin is associated with mortality in elderly people
European Journal of Clinical Investigation
Associations of ω-3 Fatty Acids with Interstitial Lung Disease and Lung Imaging Abnormalities among Adults
American Journal of Epidemiology
The power of genetic diversity in genome-wide association studies of lipids
Nature
Body weight changes and longitudinal associations with cognitive decline among community-dwelling older adults
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
A New Panel-Estimated GFR, Including β
2
-Microglobulin and β-Trace Protein and Not Including Race, Developed in a Diverse Population
American Journal of Kidney Diseases
Publisher Correction
Nature Communications
Dementia risk in the general population
European Journal of Epidemiology
Type 2 Diabetes, Physical Activity and Risk of Mild Cognitive
Impairment and Dementia in Community Dwelling Old Adults
Computed tomography-based skeletal muscle and adipose tissue attenuation
Experimental Gerontology
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
The Lancet
A proteome-wide genetic investigation identifies several sars-cov-2-exploited host targets of clinical relevance
eLife
FSH Level and Changes in Bone Mass and Body Composition in Older Women and Men
The Journal of clinical endocrinology and metabolism
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Molecular Psychiatry
The trans-ancestral genomic architecture of glycemic traits
Nature Genetics
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Nature Communications
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
eLife
Serum FSH Is Associated with BMD, Bone Marrow Adiposity, and Body Composition in the AGES-Reykjavik Study of Older Adults
Journal of Clinical Endocrinology and Metabolism
Sex-specific 25-hydroxyvitamin D threshold concentrations for functional outcomes in older adults
American Journal of Clinical Nutrition
Association of low-frequency and rare coding variants with information processing speed
Translational Psychiatry
Contributions of Cerebral Blood Flow to Associations between Blood Pressure Levels and Cognition
Hypertension
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
Nature Communications
Common variants at 12q15 and 12q24 are associated with infant head circumference
Nature Genetics
2020
Hiatus hernia and interstitial lung abnormalities
European Respiratory Journal
Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis
JAMA Cardiology
Correction to
Osteoporosis International
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose
PLoS ONE
Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function
Aging clinical and experimental research
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Nature Genetics
The genetic architecture of the human cerebral cortex
Science (New York, N.Y.)
The genetics of circulating BDNF
Brain Communications
Assessing cardiovascular risks from a mid-thigh CT image
Scientific Reports
Associations of Omega-3 Fatty acids with Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults.
American Journal of Epidemiology
Antihypertensive medications and risk for incident dementia and Alzheimer's disease
The Lancet Neurology
Quantitative 3D imaging parameters improve prediction of hip osteoarthritis outcome
Scientific Reports
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
Nature Communications
Repositioning of the global epicentre of non-optimal cholesterol
Nature
Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits
HGG advances
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
Molecular Psychiatry
Twenty-seven-year time trends in dementia incidence in Europe and the United States
Neurology
GFR in healthy aging
Journal of the American Society of Nephrology
Molecular screening of familial hypercholesterolemia in Icelanders
Scandinavian Journal of Clinical and Laboratory Investigation
Type 2 diabetes, change in depressive symptoms over time, and cerebral small vessel disease
Diabetes Care
Body size at birth and age-related macular degeneration in old age
Acta Ophthalmologica
Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry
Pharmacogenomics Journal
Cerebral small vessel disease genomics and its implications across the lifespan
Nature Communications
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes
PLoS Medicine
The associations of interstitial lung abnormalities with cancer diagnoses and mortality
The European respiratory journal
Assessing cardiovascular risks from a mid-thigh CT image: A tree-based machine learning approach using radiodensitometric distributions
Scientific Reports
Cigarette Smoking Is Associated with Lower Quadriceps Cross-sectional Area and Attenuation in Older Adults
Nicotine and Tobacco Research
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
The Lancet
Traction Bronchiectasis/Bronchiolectasis is Associated with Interstitial Lung Abnormality Mortality
European Journal of Radiology
Association of common genetic variants with brain microbleeds
Neurology
Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
PLoS ONE
Circulating protein signatures and causal candidates for type 2 diabetes
Diabetes
Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities
Stroke
Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures
Osteoporosis International
Improved brain perfusion after electrical cardioversion of atrial fibrillation
Europace
A pooled-analysis of age and sex based coronary artery calcium scores percentiles
Journal of Cardiovascular Computed Tomography
Childhood overweight and obesity and the risk of depression across the lifespan
BMC Pediatrics
Greater Bone Marrow Adiposity Predicts Bone Loss in Older Women
Journal of Bone and Mineral Research
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio
International Journal of Epidemiology
2019
Publisher Correction
Nature Genetics
Association between Unrecognized Myocardial Infarction and Cerebral Infarction on Magnetic Resonance Imaging
JAMA Neurology
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
Nature Communications
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality
Circulation
A meta-analysis of genome-wide association studies identifies multiple longevity genes
Nature Communications
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
Journal of the American College of Cardiology
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
Nature Communications
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype
Nature Genetics
Predicting health and life span with the deep plasma proteome
Nature Medicine
Dynamic sitting: Measurement and associations with metabolic health
Journal of Sports Sciences
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Nature Genetics
Serum lipids in adults with late age-related macular degeneration: a case-control study
Lipids in Health and Disease
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Neurology
Associations of autozygosity with a broad range of human phenotypes
Nature Communications
Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment
Scientific Reports
Large-scale parcellation of the ventricular system using convolutional neural networks
World Health Organization cardiovascular disease risk charts
The Lancet Global Health
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Nature Communications
Unsupervised brain lesion segmentation from MRI using a convolutional autoencoder
Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts
Nutrients
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study
PLoS ONE
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Nature Genetics
Body fat distribution on computed tomography imaging and prostate cancer risk and mortality in the AGES-Reykjavik study
Cancer
Validation of a metabolite panel for a more accurate estimation of glomerular filtration rate using quantitative LC-MS/MS
Clinical Chemistry
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
Journal of the American College of Cardiology
Imaging patterns are associated with interstitial lung abnormality progression and mortality
American Journal of Respiratory and Critical Care Medicine
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Nature Genetics
Comparability of Plasma Iohexol Clearance Across Population-Based Cohorts
American Journal of Kidney Diseases
Genetic architecture of subcortical brain structures in 38,851 individuals
Nature Genetics
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Human Molecular Genetics
Author Correction
Nature Genetics
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
American Journal of Epidemiology
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Nature Genetics
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits
European Journal of Human Genetics
Omega-3 fatty acids and genome-wide interaction analyses reveal DPP10–pulmonary function association
American Journal of Respiratory and Critical Care Medicine
Pre-diagnostic 25-hydroxyvitamin D levels and survival in cancer patients
Cancer Causes and Control
Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults
European Heart Journal
Assessment of the Relationship between Genetic Determinants of Thyroid Function and Atrial Fibrillation
JAMA Cardiology
Cardiovascular Risk Factors Associated with Venous Thromboembolism
JAMA Cardiology
Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms
Alzheimer's and Dementia
Cardiovascular risk factors and incident giant cell arteritis
Scandinavian Journal of Rheumatology
Disentangling the genetics of lean mass
American Journal of Clinical Nutrition
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes
Communications Biology
SegAE: Unsupervised white matter lesion segmentation from brain MRIs using a CNN autoencoder
NeuroImage: Clinical
Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium
American Journal of Hypertension
Distribution of cerebral microbleeds in the East and West
Neurology
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Nature Genetics
Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans
PLoS ONE
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes
Hepatology Communications
Type 2 diabetes and obesity in midlife and breast cancer risk in the Reykjavik cohort
Cancer Causes and Control
Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and Von Willebrand Factor Plasma Levels
Circulation
Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes
American Journal of Clinical Nutrition
Author Correction
Nature Communications
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)
PLoS ONE
Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels
Rheumatology International
Nýsköpun
Læknablaðið
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Nature
Structural covariability hubs in old age
NeuroImage
Serum magnesium and calcium levels in relation to ischemic stroke
Neurology
2018
Effects of Vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes
American Journal of Clinical Nutrition
Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study
Human Molecular Genetics
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Nature Communications
Heritability and genome-wide associations studies of cerebral blood flow in the general population
Journal of Cerebral Blood Flow and Metabolism
Dietary intake is associated with risk of multiple myeloma and its precursor disease
PLoS ONE
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Nature Genetics
Ný íslensk beinbrotarannsókn Hjartaverndar undirstrikar mikilvßgi verklags Landspítala aα "grípa brotin"
Laeknabladid
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Nature Genetics
Association of Unrecognized Myocardial Infarction with Long-term Outcomes in Community-Dwelling Older Adults
JAMA Cardiology
Erratum to
Nature Genetics
Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations
Pharmacogenomics Journal
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Nature Genetics
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Genome Biology
Interstitial lung abnormalities and physical function
ERJ Open Research
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
American Journal of Human Genetics
Associations between Proportion of Plasma Phospholipid Fatty Acids, Depressive Symptoms and Major Depressive Disorder. Cross-Sectional Analyses from the AGES Reykjavik Study
Journal of Nutrition, Health and Aging
Reliable quantification of marrow fat content and unsaturation level using in vivo MR spectroscopy
Magnetic Resonance in Medicine
Sex hormones are negatively associated with vertebral bone marrow fat
Bone
Cigarette smoking and hip volumetric bone mineral density and cortical volume loss in older adults
Bone
Midlife metabolic factors and prostate cancer risk in later life
International Journal of Cancer
Sex differences in the spatial distribution of bone in relation to incident hip fracture
Bone
The AGES-Reykjavik Study suggests that change in kidney measures is associated with subclinical brain pathology in older community-dwelling persons
Kidney International
Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity
Journal of Bone and Mineral Research
Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum Vitamin D with pulmonary function
British Journal of Nutrition
Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusion
Europace
Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain magnetic resonance imaging
Stroke
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Circulation. Genomic and precision medicine
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Circulation. Genomic and precision medicine
Comparison of glomerular filtration rate estimating equations derived from creatinine and cystatin C
Nephrology Dialysis Transplantation
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
PLoS ONE
Multi-ethnic genome-wide association study for atrial fibrillation
Nature Genetics
Characteristics of recurrent fractures
Osteoporosis International
Associations of Quadriceps Torque Properties with Muscle Size, Attenuation, and Intramuscular Adipose Tissue in Older Adults
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals
Pharmacogenomics Journal
Advanced quantitative methods in correlating sarcopenic muscle degeneration with lower extremity function biometrics and comorbidities
PLoS ONE
The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy
Scandinavian Journal of Gastroenterology
Interstitial lung abnormalities and self-reported health and functional status
Thorax
Clinical significance of cerebral microbleeds on MRI
International Journal of Stroke
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Nature Genetics
Predicting changes in quality of life for patients in vocational rehabilitation
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes
PLoS Medicine
Correction
PLoS ONE
Langtímahorfur sjúklinga með bráða kransæðastíflu
Læknablaðið
Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 1; peer review
Wellcome Open Research
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
American Journal of Human Genetics
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies
European Heart Journal
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants
International Journal of Epidemiology
Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø study
BMJ Open
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nature Communications
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity
Nature Communications
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
Nature Communications
Dietary habits in adolescence and midlife and risk of breast cancer in older women
PLoS ONE
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
Nature Communications
Predictors of carotid plaque progression over a 4-year follow-up in the Reykjavik REFINE-study
Atherosclerosis
Co-regulatory networks of human serum proteins link genetics to disease
Science
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Wellcome Open Research
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Nature Genetics
2017
Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction
American Journal of Epidemiology
Hjartabilun meðal eldri Íslendinga
Laeknabladid
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes
European Respiratory Journal
Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data
PLoS ONE
Large perivascular spaces visible on magnetic resonance imaging, cerebral small vessel disease progression, and risk of dementia
JAMA Neurology
Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population
Stroke
Space and location of cerebral microbleeds, cognitive decline, and dementia in the community
Neurology
The use of predictive models in dynamic treatment planning
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma
Blood advances
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
American Journal of Human Genetics
Proximal Femur Volumetric Bone Mineral Density and Mortality
Journal of Bone and Mineral Research
Omega-6 fatty acid biomarkers and incident type 2 diabetes
The Lancet Diabetes and Endocrinology
Genetic Obesity and the Risk of Atrial Fibrillation
Circulation
Úr gögnum Hjartaverndar
Laeknabladid
Úr gögnum Hjartaverndar
Laeknabladid
PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke
Circulation: Cardiovascular Genetics
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Nature Genetics
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
Nature Communications
Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification
Journal of the American College of Cardiology
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function
International Journal of Epidemiology
A novel, multiplexed targeted mass spectrometry assay for quantification of complement factor H (CFH) variants and CFH-related proteins 1–5 in human plasma
Proteomics
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions
Circulation
Differential associations between retinal signs and CMBs by location
Neurology
Early life residence, fish consumption, and risk of breast cancer
Cancer Epidemiology Biomarkers and Prevention
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function
Journal of the American Society of Nephrology
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers
Heart
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
Circulation. Cardiovascular genetics
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Nature Genetics
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016
The Lancet
Genetically determined plasma lipid levels and risk of diabetic retinopathy
Diabetes
Exome-wide association study of plasma lipids in >300,000 individuals
Nature Genetics
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk
PLoS ONE
Rare and low-frequency coding variants alter human adult height
Nature
Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease
Journal of the American Heart Association
Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium
PLoS ONE
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
PLoS Genetics
Associations of fat and muscle tissue with cognitive status in older adults
Age and Ageing
Aortic stiffness and change in glomerular filtration rate and albuminuria in older people
Nephrology Dialysis Transplantation
Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly
American Journal of Kidney Diseases
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Nature Genetics
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Nature Genetics
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Hypertension
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Nature Genetics
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
The Journal of clinical investigation
Discovery of novel heart rate-associated loci using the Exome Chip
Human Molecular Genetics
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Nature Genetics
Corrigendum
Scientific Reports
Correction
Aging
Fibrosis as measured by the biomarker, tissue inhibitor metalloproteinase-1, predicts mortality in Age Gene Environment Susceptibility-Reykjavik (AGES-Reykjavik) Study
European Heart Journal
Erratum
PLoS Genetics
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Molecular Psychiatry
Bone disease in monoclonal gammopathy of undetermined significance
Blood advances
Frailty and Risk of Cardiovascular Diseases in Older Persons
Rejuvenation Research
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals
Journal of Medical Genetics
Prevalence of heart failure in the elderly and future projections
Scandinavian Cardiovascular Journal
Imminent risk of fracture after fracture
Osteoporosis International
Long-Term Hormone Replacement Therapy Is Associated with Low Coronary Artery Calcium Levels in a Cohort of Older Women
Journal of the American Geriatrics Society
Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndrome
PLoS ONE
Genetic Improvement of Runtime and its Fitness Landscape in a Bioinformatics Application
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
Scientific Reports
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation
Nature Genetics
Allometric scaling of brain regions to intra-cranial volume
Human Brain Mapping
Novel genetic loci associated with hippocampal volume
Nature Communications
Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium
Scientific Reports
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Nature Communications
The complex genetics of gait speed
Aging
Associations of 24-hour sleep duration and CT-derived measurements of muscle and bone
Experimental Gerontology
The AGES-Reykjavik study atlases
Medical Image Analysis
Trends in the incidence of dementia
European Journal of Epidemiology
2016
Determinants of outcome of vocational rehabilitation
Work
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Nature Genetics
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants
Lancet
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Nature Genetics
Incidence and prevalence of total joint replacements due to osteoarthritis in the elderly
BMC Musculoskeletal Disorders
Identification of additional risk loci for stroke and small vessel disease
The Lancet Neurology
Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis
Circulation: Cardiovascular Genetics
The association between midlife physical activity and depressive symptoms in late life
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease
Journal of Psychiatry and Neuroscience
A century of trends in adult human height
eLife
Genetic influences on schizophrenia and subcortical brain volumes
Nature Neuroscience
Cerebrovascular Damage Mediates Relations Between Aortic Stiffness and Memory
Hypertension
Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women
Osteoporosis International
Midlife cardiovascular risk factors and late-life unrecognized and recognized myocardial infarction detect by cardiac magnetic resonance
Journal of the American Heart Association
Airflow obstruction, atherosclerosis and cardiovascular risk factors in the AGES Reykjavik study
Atherosclerosis
Influence of day length and physical activity on sleep patterns in older Icelandic men and women
Journal of Clinical Sleep Medicine
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Nature Genetics
52 Genetic Loci Influencing Myocardial Mass
Journal of the American College of Cardiology
Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women
Public Health Nutrition
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
Proceedings of the National Academy of Sciences of the United States of America
Are bone turnover markers associated with volumetric bone density, size, and strength in older men and women? The AGES–Reykjavik study
Osteoporosis International
GWAS for executive function and processing speed suggests involvement of the CADM2 gene
Molecular Psychiatry
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Nature Communications
Novel Genetic Loci Associated with Retinal Microvascular Diameter
Circulation: Cardiovascular Genetics
Seasonal changes in vitamin D-effective UVB availability in Europe and associations with population serum 25-hydroxyvitamin D
Nutrients
Late-life brain volume
Neurobiology of Aging
Prevalence and prognosis of non-ischemic patterns of late gadolinium enhancement in older adults by cardiovascular MR in the Iceland-MI study
Journal of Cardiovascular Magnetic Resonance
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease
Journal of Alzheimer's Disease
Hearing in older adults with exfoliation syndrome/exfoliation glaucoma or primary open-angle glaucoma
Acta Ophthalmologica
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Nature Communications
Physical activity and incidence of sarcopenia
Age and Ageing
Prevalence and complications of chronic kidney disease in a representative elderly population in Iceland
Nephrology Dialysis Transplantation
Left–right differences in the proximal femur’s strength of post-menopausal women
Osteoporosis International
A century of trends in adult human height
eLife
Genome-wide association study identifies 74 loci associated with educational attainment
Nature
Comparison of Handgrip and Leg Extension Strength in Predicting Slow Gait Speed in Older Adults
Journal of the American Geriatrics Society
Association of lipid-related genetic variants with the incidence of atrial fibrillation
PLoS ONE
Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness
Nature Medicine
Cardiac and Carotid Markers Link with Accelerated Brain Atrophy
Arteriosclerosis, Thrombosis, and Vascular Biology
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
Nature Genetics
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies
PLoS ONE
Shared genetic contribution to ischemic stroke and Alzheimer's disease
Annals of Neurology
Interactive graph-cut segmentation for fast creation of finite element models from clinical ct data for hip fracture prediction
Computer Methods in Biomechanics and Biomedical Engineering
Natriuretic peptides and integrated risk assessment for cardiovascular disease
The Lancet Diabetes and Endocrinology
Measurement of Circulating Phospholipid Fatty Acids
Journal of the American College of Nutrition
Association between interstitial lung abnormalities and all-cause mortality
JAMA - Journal of the American Medical Association
A novel Alzheimer disease locus located near the gene encoding tau protein
Molecular Psychiatry
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
Nature Genetics
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels
Journal of Medical Genetics
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease
PLoS Genetics
Association of Forced Vital Capacity with the Developmental Gene NCOR2
PLoS ONE
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Journal of Medical Genetics
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium
Aging Cell
Vitamin D deficiency in Europe
American Journal of Clinical Nutrition
Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants
Human Molecular Genetics
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes
Diabetes
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
American Journal of Human Genetics
Muscle Quality and Myosteatosis
American Journal of Epidemiology
Pineal gland volume assessed by MRI and its correlation with 6-sulfatoxymelatonin levels among older men
Journal of Biological Rhythms
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases
American Journal of Human Genetics
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals
American Journal of Human Genetics
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
Journal of Bone and Mineral Research
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions
Genetic Epidemiology
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics
Gene-gene Interaction Analyses for Atrial Fibrillation
Scientific Reports
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Lancet (London, England)
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nature Neuroscience
Post-stroke bacteriuria among stroke patients attending a physiotherapy clinic in Ghana: a cross-sectional study
Therapeutics and Clinical Risk Management
Trends in adult body-mass index in 200 countries from 1975 to 2014
The Lancet
Occupation as a risk factor for renal cell cancer
Scandinavian Journal of Urology
Erratum: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics
Mortality in Older Persons with Retinopathy and Concomitant Health Conditions the Age, Gene/Environment Susceptibility-Reykjavik Study
Ophthalmology
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies
PLoS Genetics
Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
Alzheimer's and Dementia
High-sensitivity cardiac troponin i is a strong predictor of cardiovascular events and mortality in the ages-reykjavik community-based cohort of older individuals
Clinical Chemistry
Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study
BMJ Open
2015
Mediation analysis of aortic stiffness and renal microvascular function
Journal of the American Society of Nephrology
Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults
American Journal of Clinical Nutrition
PLD3 variants in population studies
Nature
Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein
PLoS ONE
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
A blunted diurnal cortisol response in the lower educated does not explain educational differences in coronary heart disease
Social Science and Medicine
Segmental kidney volumes measured by dynamic contrast-enhanced magnetic resonance imaging and their association with CKD in older people
American Journal of Kidney Diseases
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C
npj Aging and Mechanisms of Disease
The association between lower educational attainment and depression owing to shared genetic effects? Results in ∼25 000 subjects
Molecular Psychiatry
Midlife Blood Pressure and Late-Life GFR and Albuminuria
American Journal of Kidney Diseases
Comparing GFR estimating equations using cystatin C and creatinine in elderly individuals
Journal of the American Society of Nephrology
Polyunsaturated fatty acids in relation to incident mobility disability and decline in gait speed; The Age, Gene/Environment Susceptibility-Reykjavik Study
European Journal of Clinical Nutrition
Modulation of genetic associations with serum urate levels by body-mass-index in humans
PLoS ONE
Cerebral small vessel disease and association with higher incidence of depressive symptoms in a general elderly population
American Journal of Psychiatry
Brain Volume as an Integrated Marker for the Risk of Death in a Community-Based Sample
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Physical activity from early adulthood and risk of prostate cancer
Cancer Prevention Research
Depression and serum 25-hydroxyvitamin D in older adults living at northern latitudes - AGES-Reykjavik Study
Journal of Nutritional Science
Aortic Stiffness and Kidney Disease in an Elderly Population
American Journal of Nephrology
Relations between aortic stiffness and left ventricular structure and function in older participants in the age, gene/environment susceptibility-reykjavik study
Circulation: Cardiovascular Imaging
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Nature Genetics
Higher Plasma Phospholipid n-3 PUFAs, but Lower n-6 PUFAs, Are Associated with Lower Pulse Wave Velocity among Older Adults
1-3
Journal of Nutrition
Carotid atherosclerosis and cardiovascular health metrics in old subjects from the AGES-Reykjavik study
Atherosclerosis
Cardiac hemodynamics are linked with structural and functional features of brain aging
Journal of the American Heart Association
Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI
Circulation: Cardiovascular Genetics
Carotid arterial stiffness and risk of incident cerebral microbleeds in older people
Arteriosclerosis, Thrombosis, and Vascular Biology
Cod liver oil consumption at different periods of life and bone mineral density in old age
British Journal of Nutrition
Common genetic variants influence human subcortical brain structures
Nature
Age-related macular degeneration and mortality in community-dwelling elders
Ophthalmology
Lifetime risk of stage 3–5 CKD in a community-based sample in Iceland
Clinical Journal of the American Society of Nephrology
Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults
Journal of Nutrition
Circadian clock genes and risk of fatal prostate cancer
Cancer Causes and Control
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Nature Communications
Convergent genetic and expression data implicate immunity in Alzheimer's disease
Alzheimer's and Dementia
Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults
Obesity Reviews
Genome-wide studies of verbal declarative memory in nondemented older people
Biological Psychiatry
Fat distribution and mortality
Obesity
Genome-wide association study of kidney function decline in individuals of European descent
Kidney International
Feasibility of Using Pseudo-Continuous Arterial Spin Labeling Perfusion in a Geriatric Population at 1.5 Tesla
PLoS ONE
Sex-specific predictors of hearing-aid use in older persons
International Journal of Audiology
Risk factors associated with incident cerebral microbleeds according to location in older people
JAMA Neurology
Overweight and obesity in midlife and brain structure and dementia 26 years later
American Journal of Epidemiology
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
Circulation
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture
Nature
Genetic studies of body mass index yield new insights for obesity biology
Nature
Directional dominance on stature and cognition in diverse human populations
Nature
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Nature Genetics
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics
Covariate-adjusted measures of discrimination for survival data
Biometrical Journal
Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair
Obstetrical and Gynecological Survey
Muscle quality and muscle fat infiltration in relation to incident mobility disability and gait speed decline
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Genetic contributions to variation in general cognitive function
Molecular Psychiatry
Molecular mechanisms underlying variations in lung function
The Lancet Respiratory Medicine
White Matter Lesion Progression
Stroke
Salivary cortisol, brain volumes, and cognition in community-dwelling elderly without dementia
Neurology
New genetic loci link adipose and insulin biology to body fat distribution
Nature
Urinary melatonin levels, sleep disruption, and risk of prostate cancer in elderly men
European Urology
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis
The Lancet Diabetes and Endocrinology
Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease
PLoS ONE
N-terminal pro-brain natriuretic peptide and abnormal brain aging
Neurology
Integrative pathway genomics of lung function and airflow obstruction
Human Molecular Genetics
Novel loci associated with usual sleep duration
Molecular Psychiatry
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension
PLoS Genetics
2014
Adipose tissue density, a novel biomarker predicting mortality risk in older adults
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX
Osteoporosis International
Glycated hemoglobin measurement and prediction of cardiovascular disease
JAMA - Journal of the American Medical Association
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese
Journal of the American College of Cardiology
Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations
American Journal of Human Genetics
Gene-age interactions in blood pressure regulation
American Journal of Human Genetics
Polygenic scores associated with educational attainment in adults predict educational achievement and ADHD symptoms in children
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
Association of low-density lipoprotein cholesterol - Related genetic variants with aortic valve calcium and incident aortic stenosis
JAMA - Journal of the American Medical Association
Genetic diversity is a predictor of mortality in humans
BMC Genetics
Milk consumption throughout life and bone mineral content and density in elderly men and women
Osteoporosis International
Assessment of incident spine and hip fractures in women and men using finite element analysis of CT scans
Journal of Bone and Mineral Research
The alcohol paradox
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Erratum
Osteoporosis International
Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008
Osteoporosis International
The prevalence of aortic stenosis in the elderly in Iceland and predictions for the coming decades
International Journal of Cardiology
Profile and health-related quality of life of Ghanaian stroke survivors
Clinical Interventions in Aging
Five-year incidence, progression, and risk factors for age-related macular degeneration
Ophthalmology
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Nature Genetics
Pulse pressure relation to aortic and left ventricular structure in the age, gene/environment susceptibility (AGES)-reykjavik study
Hypertension
Genetic determinants of heel bone properties
Human Molecular Genetics
Joint effect of mid- and late-life blood pressure on the brain
Neurology
Longitudinal and circumferential strain of the proximal aorta
Journal of the American Heart Association
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk
Europace
Community awareness of stroke in Accra, Ghana
BMC Public Health
Defining the role of common variation in the genomic and biological architecture of adult human height
Nature Genetics
Inflammatory cytokines and risk of coronary heart disease
European Heart Journal
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
American Journal of Human Genetics
Population assessment of future trajectories in coronary heart disease mortality
PLoS ONE
Structural MRI correlates of apathy symptoms in older persons without dementia
Neurology
Adipose tissue, muscle, and function
Diabetes Care
Spousal loss and cognitive function in later life
American Journal of Epidemiology
Impairments in hearing and vision impact on mortality in older people
Age and Ageing
Rannsóknarstöd hjartaverndar, fortíd og nútíd
Laeknabladid
Serum carboxymethyllysine, an advanced glycation end product, and age-related macular degeneration
JAMA Ophthalmology
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
Nature Genetics
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
Nature Communications
Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation
Circulation
Midlife migraine and late-life parkinsonism
Neurology
The challenges of genome-wide interaction studies
PLoS ONE
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Nature
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function
PLoS ONE
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease
PLoS ONE
Circulating sclerostin associated with vertebral bone marrow fat in older men but not women
Journal of Clinical Endocrinology and Metabolism
Fracture risk assessment in older adults using a combination of selected quantitative computed tomography bone measures
Journal of Clinical Densitometry
Diabetes, markers of brain pathology and cognitive function
Annals of Neurology
Hip fractures and bone mineral density in the elderly - Importance of serum 25-hydroxyvitamin D
PLoS ONE
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
American Journal of Human Genetics
Drug-gene interactions and the search for missing heritability
Pharmacogenomics Journal
Longitudinal changes in size and composition of carotid artery plaques using ultrasound
Journal for Vascular Ultrasound
Different susceptibility of medial temporal lobe and basal ganglia atrophy rates to vascular risk factors
Neurobiology of Aging
Birth size and brain function 75 years later
Pediatrics
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index
PLoS Genetics
Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels
Circulation. Cardiovascular genetics
Multi-ethnic fine-mapping of 14 central adiposity loci
Human Molecular Genetics
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality
Nutrition, Metabolism and Cardiovascular Diseases
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
Human Molecular Genetics
Assessing risk prediction models using individual participant data from multiple studies
American Journal of Epidemiology
2013
Persistence of the effect of birth size on dysglycaemia and type 2 diabetes in old age
Age
Discovery and refinement of loci associated with lipid levels
Nature Genetics
Changes in total cholesterol levels in Western societies are not related to statin, but rather dietary factors
European Heart Journal
Copy Number Variations in Alternative Splicing Gene Networks Impact Lifespan
PLoS ONE
Genetic Loci for Retinal Arteriolar Microcirculation
PLoS ONE
Prevalence of airflow obstruction in nonsmoking older individuals using different spirometric criteria
COPD: Journal of Chronic Obstructive Pulmonary Disease
Associations of current and remitted major depressive disorder with brain atrophy
Psychological Medicine
Socioeconomic factors from midlife predict mobility limitation and depressed mood three decades later; findings from the AGES-Reykjavik Study.
BMC Public Health
Midlife physical activity preserves lower extremity function in older adults
Journal of the American Geriatrics Society
Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults
Journal of Clinical Endocrinology and Metabolism
Best Practices and Joint Calling of the HumanExome BeadChip
PLoS ONE
Genome-wide association study meta-analysis of chronic widespread pain
Annals of the Rheumatic Diseases
N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events
European Heart Journal
Erratum
European Heart Journal
Áhrif 6 mánaða fjölþættrarþjálfunar á hreyfigetu, vöðvakraft, þol og líkamsþyngdarstuðul eldri einstaklinga. Eru áhrif þjálfunar sambærileg hjá konum og körlum?
Læknabladid
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk
Molecular Psychiatry
Effects of exercise training and nutrition counseling on body composition and cardiometabolic factors in old individuals
European Geriatric Medicine
The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes
PLoS ONE
Genome-Wide Association Study of Retinopathy in Individuals without Diabetes
PLoS ONE
Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population
Journal of the American Heart Association
CRP is associated with lung function decline in men but not women
Respiratory Medicine
A genome-wide association study of depressive symptoms
Biological Psychiatry
Genetic associations with valvular calcification and aortic stenosis
New England Journal of Medicine
Large-scale association analysis identifies new risk loci for coronary artery disease
Nature Genetics
Similar decline in mortality rate of older persons with and without type 2 diabetes between 1993 and 2004 the Icelandic population-based Reykjavik and AGES-Reykjavik cohort studies
BMC Public Health
Erratum
Nature Genetics
Consumption of Fish Products across the Lifespan and Prostate Cancer Risk
PLoS ONE
Common variants associated with plasma triglycerides and risk for coronary artery disease
Nature Genetics
Pulmonary function impairment may be an early risk factor for late-life cognitive impairment
Journal of the American Geriatrics Society
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura
Cephalalgia
Proximal femoral density distribution and structure in relation to age and hip fracture risk in women
Journal of Bone and Mineral Research
Genetic variation associated with circulating monocyte count in the eMERGE Network
Human Molecular Genetics
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
Nature Genetics
Candidate gene association study of bmi-related loci, weight, and adiposity in old age
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
The Molecular Genetic Architecture of Self-Employment
PLoS ONE
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease
Cell
Similarities and differences between sexes in regional loss of cortical and trabecular bone in the mid-femoral neck
Journal of Bone and Mineral Research
Common variants in mendelian kidney disease genes and their association with renal function
Journal of the American Society of Nephrology
Hemostatic Factors and Risk of Coronary Heart Disease in General Populations
PLoS ONE
Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration
PLoS ONE
Sleep disruption among older men and risk of prostate cancer
Cancer Epidemiology Biomarkers and Prevention
Lack of association between the MTHFR C677T variant and migraine with aura in an older population
Cephalalgia
Erratum
Nature Genetics
Association of type D personality with unhealthy lifestyle, and estimated risk of coronary events in the general Icelandic population.
European Journal of Preventive Cardiology
Erratum
European Heart Journal
Atrial fibrillation is associated with reduced brain volume and cognitive function independent of cerebral infarcts
Stroke
Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations
PLoS Genetics
Association of heat shock proteins with all-cause mortality
Age
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
Nature Genetics
Causal Relationship between Obesity and Vitamin D Status
PLoS Medicine
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Science
Early peak height velocity and cardiovascular disease mortality among Icelandic women
Annals of Medicine
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Nature Genetics
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Nature Genetics
Coronary artery calcium and physical performance as determinants of mortality in older age
International Journal of Cardiology
Stefnumörkun í heilbrigðismálum: leiðin til lýðheilsu.
Laeknabladid
A genome-wide association study of early menopause and the combined impact of identified variants
Human Molecular Genetics
Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?
PLoS ONE
Serum vitamin D and parathyroid hormone in relation to cardiac structure and function
Journal of Clinical Endocrinology and Metabolism
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent
American Journal of Epidemiology
Migraine, depression, and brain volume
Neurology
Structural patterns of the proximal femur in relation to age and hip fracture risk in women
Bone
Erratum
Nature Genetics
2012
Milk intake in early life and risk of advanced prostate cancer
American Journal of Epidemiology
Retinopathy in old persons with and without diabetes mellitus
Diabetologia
Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults
JAMA - Journal of the American Medical Association
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
Nature Genetics
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Nature Genetics
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women
PLoS Genetics
Tengsl búsetu fyrstu 20 æviárin við áhættu á sykursýki af tegund 2
Laeknabladid
FTO genotype is associated with phenotypic variability of body mass index
Nature
Brain tissue volumes in the general population of the elderly. The AGES-Reykjavik Study.
NeuroImage
Evaluation of the postural stability of elderly persons using time domain signal analysis
Journal of Vestibular Research: Equilibrium and Orientation
Genetic, physiological, and lifestyle predictors of mortality in the general population
American Journal of Public Health
The promises and pitfalls of genoeconomics
Annual Review of Economics
Lipid-related markers and cardiovascular disease prediction
JAMA - Journal of the American Medical Association
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM
Molecular Psychiatry
Common variants at 6q22 and 17q21 are associated with intracranial volume
Nature Genetics
Interleukin-6 receptor pathways in coronary heart disease
The Lancet
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Nature Genetics
Effects of a 6-month multimodal training intervention on retention of functional fitness in older adults
International Journal of Behavioral Nutrition and Physical Activity
Effect of Birth Year on Birth Weight and Obesity in Adulthood
PLoS ONE
Mid-thigh cortical bone structural parameters, muscle mass and strength, and association with lower limb fractures in older men and women (AGES-Reykjavik Study)
Calcified Tissue International
Coronary artery calcium distributions in older persons in the AGES-reykjavik study
European Journal of Epidemiology
Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements
PLoS ONE
Common genetic variation in the 3β-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk the aortagen consortium
Circulation: Cardiovascular Genetics
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function
PLoS Genetics
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
American Journal of Respiratory and Critical Care Medicine
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study
Age and Ageing
Lifelong physical activity in maintaining bone strength in older men and women of the Age, Gene/environment susceptibility-reykjavik study
Osteoporosis International
Brain tissue volumes by APOE genotype and leisure activity-the AGES-Reykjavik Study
Neurobiology of Aging
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Nature Genetics
Identification of common variants associated with human hippocampal and intracranial volumes
Nature Genetics
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Nature Genetics
Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans-A descriptive epidemiologic study
Prostaglandins Leukotrienes and Essential Fatty Acids
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function
Human Molecular Genetics
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations
Nature Genetics
Erratum
Nature Genetics
Langvinnir sjúkdómar
Laeknabladid
Adult height and the risk of cause-specific death and vascular morbidity in 1 million people
International Journal of Epidemiology
Rye bread consumption in early life and reduced risk of advanced prostate cancer
Cancer Causes and Control
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
Human Genetics
Genome-wide meta-analysis of common variant differences between men and women
Human Molecular Genetics
C-reactive protein, fibrinogen, and cardiovascular disease prediction
New England Journal of Medicine
Cerebral microbleeds and age-related macular degeneration
Neurobiology of Aging
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function
PLoS Genetics
2011
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction
Circulation
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Nature Genetics
CUBN is a gene locus for albuminuria
Journal of the American Society of Nephrology
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
PLoS Genetics
Association of hypertension drug target genes with blood pressure and hypertension in 86 588 individuals
Hypertension
Associations of visceral and liver fat with the metabolic syndrome across the spectrum of obesity
Obesity
N-terminal pro-brain natriuretic peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease
Journal of the American College of Cardiology
Multiple loci are associated with white blood cell phenotypes
PLoS Genetics
Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik Study
BMJ Open
Association between C reactive protein and coronary heart disease
BMJ
Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes
Investigative Ophthalmology and Visual Science
Erratum
Nature Genetics
High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men
European Journal of Preventive Cardiology
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque
Nature Genetics
Improving the prediction of incident atrial fibrillation
Archives of Internal Medicine
Prevalence of age-related macular degeneration in old persons
Ophthalmology
A genome-wide association study of aging
Neurobiology of Aging
Physical activity attenuates the influence of FTO variants on obesity risk
PLoS Medicine
Arterial stiffness, pressure and flow pulsatility and brain structure and function
Brain
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels
Circulation
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Nature Genetics
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Nature Genetics
Childhood growth and adult hypertension in a population of high birth weight
Hypertension
Personalized Epigenomic Signatures That Are Stable over Time and Covary with Body Mass Index (Science Translational Medicine (2011) 3, (65er1))
Science Translational Medicine
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Diabetes
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
Nature Genetics
Validity of retrospective diet history
Journal of Nutrition, Health and Aging
RANTES/CCL5 and risk for coronary events
PLoS ONE
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Nature
A genome-wide association study of aging
Neurobiology of Aging
Distribution of cortical bone in the femoral neck and hip fracture
Bone
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease
Circulation: Cardiovascular Genetics
Meta-analysis of genome-wide association for migraine in six population-based European cohorts
European Journal of Human Genetics
Diabetes mellitus, fasting glucose, and risk of cause-specific death
New England Journal of Medicine
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
American Journal of Human Genetics
Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projections
Europace
Genome-wide association studies of cerebral white matter lesion burden
Annals of Neurology
2010
Migraine with aura and risk of cardiovascular and all cause mortality in men and women
BMJ (Online)
Effect of rheumatoid factor on mortality and coronary heart disease
Annals of the Rheumatic Diseases
A Meta-analysis of four genome-wide association studies of survival to age 90 years or older
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Nature Genetics
Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung function
BMC Pulmonary Medicine
Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality
BMJ (Online)
Genome-wide association studies of mri-defined brain infarcts
Stroke
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
Nature Genetics
Markers of dysglycaemia and risk of coronary heart disease in people without diabetes
PLoS Medicine
Validation of an atrial fibrillation risk algorithm in Whites and African Americans
Archives of Internal Medicine
NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors
Atherosclerosis
Myocardial structure and function by echocardiography in relation to glucometabolic status in elderly subjects from 2 population-based cohorts
American Heart Journal
New loci associated with kidney function and chronic kidney disease
Nature Genetics
IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes
Growth Hormone and IGF Research
Genome-wide association analysis identifies multiple loci related to resting heart rate
Human Molecular Genetics
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six loci influencing serum magnesium levels
PLoS Genetics
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels
Human Molecular Genetics
Genome-wide association study of PR interval
Nature Genetics
Coronary artery calcium, brain function and structure
Stroke
Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivo
PLoS Genetics
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors
Circulation: Cardiovascular Genetics
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
Nature Genetics
Correlation of echocardiographic findings with cerebral infarction in elderly adults
Stroke
Analysing the large decline in coronary heart disease mortality in the icelandic population aged 25-74 between the years 1981 and 2006
PLoS ONE
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Nature Genetics
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Nature
Uromodulin levels associate with a common UMOD variant and risk for incident CKD
Journal of the American Society of Nephrology
Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women
Neurobiology of Aging
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies
Lancet
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality
The Lancet
Common variants in KCNN3 are associated with lone atrial fibrillation
Nature Genetics
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms
Circulation
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies
International Journal of Epidemiology
Personalized epigenomic signatures that are stable over time and covary with body mass index
Science Translational Medicine
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease
The Lancet
Genome-wide analysis of genetic loci associated with Alzheimer disease
JAMA - Journal of the American Medical Association
The effect of midlife physical activity on cognitive function among older adults
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
2009
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche
Nature Genetics
Cardiovascular genetics in Iceland
European Heart Journal
Unfavourable risk factors for type 2 diabetes mellitus are already apparent more than a decade before onset in a population-based study of older persons
European Journal of Epidemiology
Glycemic status and brain injury in older individuals
Diabetes Care
Þróun holdafars og sykursýki í 40 ár á íslandi
Laeknabladid
Major lipids, apolipoproteins, and risk of vascular disease
JAMA
Abnormal T-wave axis is associated with coronary artery calcification in older adults
Scandinavian Cardiovascular Journal
Migraine headache in middle age and late-life brain infarcts
JAMA - Journal of the American Medical Association
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium design of prospective meta-analyses of genome-wide association studies from 5 Cohorts
Circulation: Cardiovascular Genetics
Genome-wide association study of blood pressure and hypertension
Nature Genetics
Genome-wide association meta-analysis for total serum bilirubin levels
Human Molecular Genetics
Cerebral infarcts and cognitive performance importance of location and number of infarcts
Stroke
Variants in ZFHX3 are associated with a trial fibrillation in individuals of European ancestry
Nature Genetics
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality
JAMA
Multiple loci associated with indices of renal function and chronic kidney disease
Nature Genetics
Lipoprotein(a)
Current Opinion in Cardiology
Ventricular dilation
Annals of Neurology
Microvascular lesions in the brain and retina
Annals of Neurology
B-type natriuretic peptides and cardiovascular risk
Circulation
Migraine headache in middle age and late-life brain infarcts
Obstetrical and Gynecological Survey
C-reactive protein in migraine sufferers similar to that of non-migraineurs
Cephalalgia
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Nature Genetics
The interaction of adiposity with the CRP gene affects CRP levels
International Journal of Obesity
NRXN3Is a novel locus for waist circumference
PLoS Genetics
2008
Cognitive impairment
American Journal of Epidemiology
Retinal and cerebral microvascular signs and diabetes the age, gene/environment susceptibility-reykjavik study
Diabetes
Early discharge and home intervention reduces unit costs after total hip replacement
International Journal of Health Care Finance and Economics
Genoeconomics
Long-term interleukin-6 levels and subsequent risk of coronary heart disease
PLoS Medicine
The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II
Journal of Molecular Medicine
Birth weight and risk of type 2 diabetes a systematic review
JAMA - Journal of the American Medical Association
White matter lesions and cognitive performance
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Hemodynamics of increased pulse pressure in older women in the community-based age, gene/environment susceptibility-Reykjavik study
Hypertension
Einkenni og teikn fótameins hjá íslenskum sjúklingum meǒ sykursýki af tegund 2
Laeknabladid
Lipoprotein(a) levels and risk of future coronary heart disease
Archives of Internal Medicine
Localized measures of callosal atrophy are associated with late-life hypertension
NeuroImage
Intra-individual change over time in DNA methylation with familial clustering
JAMA - Journal of the American Medical Association
2007
Circulating concentrations of insulin markers and coronary heart disease
European Heart Journal
Protein expression within the human renal cortex and renal cell carcinoma
Cell Preservation Technology
Optimum expression of adult lung function based on all-cause mortality
Respiratory Medicine
Monoclonal gammopathy
Haematologica
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases
European Journal of Epidemiology
Forspárgildi QRS útslaga á hjartalínuriti, Minnesota-líkanid, un dánartídni karla. Reykjavíkurrannsókn Hjartaverndar.
Læknabladid
Algengi sykursýki af tegund tvö á Islandi 1967-2002.
Læknabladid
Renal function and risk of coronary heart disease in general populations
PLoS Medicine
Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation project
European Journal of Preventive Cardiology
Increasing glucose levels and BMI predict future heart failure. Experience from the Reykjavík Study
European Journal of Heart Failure
Population-based register of acute myocardial infarction
European Journal of Cardiovascular Prevention and Rehabilitation
Triglycerides and the risk of coronary heart disease
Circulation
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Nature Genetics
Infant feeding patterns and midlife erythrocyte sedimentation rate
Acta Paediatrica, International Journal of Paediatrics
Age, gene/environment susceptibility-reykjavik study
American Journal of Epidemiology
Inaccuracy in self-report of fractures may underestimate association with health outcomes when compared with medical record based fracture registry
European Journal of Epidemiology
Nordic biological specimen banks as basis for studies of cancer causes and control - More than 2 million sample donors, 25 million person years and 100 000 prospective cancers
Acta Oncologica
2006
Increasing sex difference in bone strength in old age
Bone
Examination of genetic effects of polymorphisms in the MCP-1 and CCR2 genes on MI in the Icelandic population
Atherosclerosis
Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanisms
Atherosclerosis
Skaðleg áhrif reykinga á heilsufar hafa verið verulega vanmetin. Niðurstöður úr hóprannsóknum Hjartaverndar
Læknabladid
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Nature Genetics
Genetic Screening in Populations
2005
Serum uric acid and coronary heart disease in 9,458 incident cases and 155,084 controls
PLoS Medicine
Reducing costs after total hip replacement
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk
Journal of Experimental Medicine
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment
Circulation
Glucose abnormalities and heart failure predict poor prognosis in the population-based Reykjavík Study
European Journal of Cardiovascular Prevention and Rehabilitation
Prevalence of chronic kidney disease based on estimated glomerular filtration rate and proteinuria in Icelandic adults
Nephrology Dialysis Transplantation
Erratum
Nature Genetics
Mótefnatengd sykursýki af tegund 2 á Islandi
Læknabladid
The association between glucose abnormalities and heart failure in the population-based Reykjavík Study
Diabetes Care
Short hospital stay augmented with education and home-based rehabilitation improves function and quality of life after hip replacement
Acta Orthopaedica
2004
Association between size at birth, truncal fat and obesity in adult life and its contribution to blood pressure and coronary heart disease; study in a high birth weight population
European Journal of Clinical Nutrition
C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease
New England Journal of Medicine
The absolute risk of recurrent myocardial infarction is similar amongst both sexes
European Journal of Preventive Cardiology
Familial risk of lung carcinoma in the Icelandic population
Journal of the American Medical Association
C-reactive protein and coronary heart disease [1] (multiple letters)
New England Journal of Medicine
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
Nature Genetics
Loss of teeth and coronary heart disease
International Journal of Prosthodontics
2003
Áhættuþættir hjarta- og æðasjúkdóma meðal fimmtugra á Akureyri og í Hafnarfirði : staða og áhrif einfaldrar íhlutunar
Læknablaðið
Family history of myocardial infarction increases the risk of coronary heart disease, independent of other risk factors
Evidence-based Cardiovascular Medicine
Systematic family screening for familial hypercholesterolemia in Iceland
Arteriosclerosis, Thrombosis, and Vascular Biology
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
Nature Genetics
Erythrocyte Sedimentation Rate, an Independent Predictor of Coronary Heart Disease in Men and Women
American Journal of Epidemiology
Subclinical intestinal inflammation
Gastroenterology
Notkun náttúruefna, fæðubótarefna og lausasölulyfja : hönnun og prófun spurningalista
Læknablaðið
Breytingar á reykingavenjum miðaldra og eldri Íslendinga síðastliðin þrjátíu ár og ástæður þeirra : niðurstöður úr hóprannsóknum Hjartaverndar
Læknablaðið
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2
American Journal of Human Genetics
2002
Size at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight population
American Journal of Clinical Nutrition
Localization of a susceptibility gene for common forms of stroke to 5q12
American Journal of Human Genetics
Localization of a gene for peripheral arterial occlusive disease to chromosome 1p31
American Journal of Human Genetics
Declining coronary heart disease mortality in Iceland
Scandinavian Cardiovascular Journal
Do lipids, blood pressure, diabetes, and smoking confer equal risk of myocardial infarction in women as in men? The Reykjavik Study
European Journal of Cardiovascular Prevention & Rehabilitation
Size at birth and coronary artery disease in a population with high birth weight
American Journal of Clinical Nutrition
Fifteen percent of myocardial infarctions and coronary revascularizations explained by family history unrelated to conventional risk factors
European Heart Journal
Relationship between size at birth and hypertension in a genetically homogenous population of high birth weight
Journal of Hypertension
2001
Arfbundin kólesterólhækkun : yfirlit yfir stöðu þekkingar og árangur markvissrar leitar á Íslandi
Læknablaðið
The -629C > A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men
Atherosclerosis
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men
Thrombosis and Haemostasis
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study
Atherosclerosis
Þróun ofþyngdar og offitu meðal 45-64 ára Reykvíkinga á árunum 1975-1994
Læknablaðið
Breytingar á tíðni kransæðasjúkdóma á Íslandi
Læknablaðið
Hómócystein, fólat og kóbalamín í íslenskum konum og körlum
Læknablaðið
2000
Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are predictors of plasma cholesterol response to dietary change
Atherosclerosis
Treatment with different doses of folic acid in haemodialysis patients
Nephrology Dialysis Transplantation
1999
Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations
European Journal of Clinical Investigation
The genetic determinants of hyper-lipidaemia
Erythrocyte sedimentation rate (esr) as a predictor of cardiovascular death. the reykjavik study
Scandinavian Cardiovascular Journal, Supplement
Hyperhomocysteinaemia, genetics and cardiovascular disease risk
European Heart Journal
The type of mutation in the low density lipoprotein receptor gene influences the cholesterol-lowering response of the HMG-CoA reductase inhibitor simvastatin in patients with heterozygous familial hypercholesterolaemia
Atherosclerosis
The asp9 to asm polymorphism in lipoprotein lipase affects plasma triglyceride levels but not the risk of developing ml in the homogenous icelandic population
Scandinavian Cardiovascular Journal, Supplement
A common polymorphism in the cholesteryl ester transfer protein gene affects plasma hdl concentration and the risk of myocardial infarction in the homogenous icelandic population
Scandinavian Cardiovascular Journal, Supplement
1998
Detection of the low density lipoprotein receptor gene PvuII intron 15 polymorphism using the polymerase chain reaction
Disease Markers
Linkage disequilibrium at the cystathionine β synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine
Annals of Human Genetics
C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR)
Atherosclerosis
1997
Variation at the lipoprotein lipase and apolipoprotein AI-CIII gene loci are associated with fasting lipid and lipoprotein traits in a population sample from Iceland
Genetic Epidemiology
Common founder mutation in the LDL receptor gene causing familial hypercholesterolaemia in the Icelandic population
Human Mutation
Interaction of the cholesteryl ester transfer protein I405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentration
Clinical Genetics
Single-strand conformation polymorphism analysis with high throughput modifications, and its use in mutation detection in familial hypercholesterolemia
Clinical Chemistry
The usefulness of three biallelic restriction fragment length polymorphisms versus a polymorphic dinucleotide tandem repeat polymorphism at the low-density-lipoprotein receptor gene locus for diagnosis of familial hypercholesterolemia
Disease Markers
Single-strand conformation polymorphism analysis with high throughput modifications, and its use in mutation detection in familial hypercholesterolemia. The IFCC Scientific Division
Journal of the International Federation of Clinical Chemistry / IFCC
Spectrum of LDL receptor gene mutations in heterozygous familial hypercholesterolemia
Human Mutation
1996
Use of the single strand conformation polymorphism method for rapid screening for mutations in the low density lipoprotein receptor gene in patients with familial hypercholesterolemia
Zeitschrift für Gastroenterologie
High throughput modifications of single-strand conformation polymorphism analysis : mutation detection in familial hypercholesterolemia
1995
Dried template DNA, dried PCR oligonucleotides and mailing in 96-well plates
BioTechniques
Response to drugs and diet in a compound heterozygote for familial hypercholesterolaemia
Archives of Disease in Childhood
Utilities for high throughput use of the single strand conformational polymorphism method
Journal of Medical Genetics
SSCP analysis and DNA sequencing for genetic characterization of a multi-allelic disorder, familial hypercholesterolaemia
Effect of the StuI polymorphism in the LDL receptor gene (Ala 370 to Thr) on lipid levels in healthy individuals
Clinical Genetics
1994
Effect on plasma lipid levels of different classes of mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia
Arteriosclerosis, Thrombosis, and Vascular Biology
Handling of large (300 x 400 mm), thin (0.4 mm) polyacrylamide gels and recovery as dried gels
BioTechniques
1993
Identification of recurrent and novel mutations in exon 4 of the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom
Arteriosclerosis and Thrombosis
Six DNA polymorphisms in the low density lipoprotein receptor gene
Journal of Medical Genetics
Use of the single-strand conformational polymorphism method to detect recurrent and novel mutations in the low-density lipoprotein repeptor gene in patients with familial hypercholesterolaemia
The Clinical Investigator
Identification of common genetic polymorphisms that determine plasma levels of ApoAI and HDL-C
Atherosclerosis
The molecular genetics of pediatric lipid disorders
Pediatric Research
ASSOCIATION OF APOLIPOPROTEIN-E POLYMORPHISM WITH PLASMA-LEVELS OF HIGH-DENSITY-LIPOPROTEIN AND LIPOPROTEIN(A), AND EFFECT OF DIET IN HEALTHY-MEN AND WOMEN
Nutrition Metabolism and Cardiovascular Diseases
1992
Interaction between a polymorphism of the apo A-I promoter region and smoking determines plasma levels of HDL and apo A-I
Arteriosclerosis and Thrombosis
Characterization of deletions in the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom
Arteriosclerosis and Thrombosis
Þéttni fituprótína í Íslendingum
Læknablaðið
1991
PCR-based method to create a specific mutation as a reference for oligomelting
Clinical Chemistry
Identification of the 664 proline to leucine mutation in the low density lipoprotein receptor in four unrelated patients with familial hypercholesterolaemia in the UK
Clinical Genetics
1990
Kólesteról í blóði : áhrif erfðaþátta
Læknablaðið
1989
Polymorphism of the c‐Ha‐ras‐1 proto‐oncogene in sporadic and familial breast cancer
International Journal of Cancer
A study of familial hypercholesterolemia in Iceland using RFLPs
Journal of Medical Genetics
1987
Specific polypeptide differences in normal versus malignant human breast tissues by two-dimensional electrophoresis
Breast Cancer Research and Treatment
1986
Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.
Journal of General Microbiology
1985
Suppression of temperature sensitive mutations in oncogene-related CDC genes in Saccharomyces cerevisiae by catabolite repression resistance and cytoplasmic petite mutations
Current Genetics
1984
Isoenzyme pattern and subcellular localization of hexokinases in human breast cancer and nonpathological breast tissue
International Journal of Cancer
Keywords for Specialisation:
Genetic epidemiology
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EPOS Ísland
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Heimsmarkmiðin
1. Engin fátækt
2. Ekkert hungur
3. Heilsa og vellíðan
4. Menntun fyrir alla
5. Jafnrétti kynjanna
6. Hreint vatn og hreinlætisaðstaða
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14. Líf í vatni
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17. Samvinna um markmiðin
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Viðburðaröð
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Háskólavinir
Fréttabréf Háskólavina
Spurt og svarað
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Um Vísinda- og nýsköpunarsvið
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Rannsóknasjóðir doktorsnema
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Austurland
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ADVENT
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BuSK
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SCITOUR: Scientific Tourism
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Worlds of Related Coercions in Work (WORCK)
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ROCS rannsóknastofnunin
Stýrihópur HÍ og LSH
COVID rannsóknir og fræði
Nám
Námsframboð
Leita að námi A-Ö
Örnám A-Ö
Fjarnám
Hvað er fjarnám?
MBA nám
Endurmenntun HÍ
Annað nám
Skiptinám
Umsókn um skiptinám
Áfangastaðir
Styrkir og fjármögnun
Styrkir og fjármögnun
Erasmus+
Erasmus+ styrkir til landa utan ESB
Nordic Centre
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Skilyrði fyrir skiptinámi
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Viltu verða mentor?
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Hvað segja skiptinemar?
Rafrænn námssamningur vegna lengri dvala
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Um starfsþjálfun
Hvernig finn ég starfsþjálfunartækifæri?
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Umsókn um starfsþjálfun
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Sumarnám
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Erasmus+ dvöl innan Evrópu
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Alþjóðavikur
Nám á eigin vegum
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Á ég rétt á aðstoð?
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Veröld - hús Vigdísar
VR-I
VR-II
VR-III
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Íþróttahús
Bílastæði
Lífið í HÍ
Félagslíf
Matsala og kaffistofur
Stúdentaíbúðir
Leikskólar
Samgöngur