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Forsíða

Sigrún Helga Lund - Professor

Sigrún Helga Lund

–

School of Engineering and Natural Sciences

Sigrún Helga LundHún/Hennar

Professor

Location
Tæknigarður / Tg-313
Phone
525 - 4636
Email
sigrunhl [at] hi.is

Unit
Faculty of Physical Sciences

Published works

2026

Atrial Fibrillation, Anticoagulants, and CRC OutcomesThrombosis and Haemostasis

2025

Effects of aspirin at diagnosis on the survival of colorectal cancer patientsScandinavian Journal of Gastroenterology
Associations of healthy lifestyle and genetic susceptibility with risks of osteoarthritisRheumatology
Limited utility of endoscopy in young patients without alarm featuresScandinavian Journal of Gastroenterology
Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With SepsisLiver International
Pituitary Dysfunction Following Mild Traumatic Brain Injury in Female Athletes: Neuropsychological and Psychological FindingsNeuroRehabilitation: An International, Interdisciplinary Journal
ICD-10 code validation for gastrointestinal bleeding in patients receiving oral anticoagulationBMC Gastroenterology
Identification of Distinguishing Features of Drug-Induced Liver Injury and Liver Injury Associated With SepsisLiver International
Túlkun marktækni þegar öryggisbil skarastLaeknabladid
Region-based U-nets for fast, accurate, and scalable deep brain segmentationNeuroImage: Clinical
Pituitary Dysfunction Following Mild Traumatic Brain Injury in Female AthletesNeuroRehabilitation
Hvaða afl er þér efst í huga?Laeknabladid
Low incidence of thromboembolism with Fiix-monitored warfarin compared to conventional warfarin and DOACs in patients with AFBlood Vessels, Thrombosis and Hemostasis

2024

Góð ráð við gerð töflu 1Læknablaðið
The correlation between CpG methylation and gene expression is driven by sequence variantsNature Genetics
Variants at the Interleukin 1 Gene Locus and PericarditisJAMA Cardiology
Correction toNature
Pituitary dysfunction following mild traumatic brain injury in female athletesEndocrine Connections
Hinar fjóru gerðir breyta og myndræn framsetning þeirraLæknablaðið
Antiviral Treatment and Risk of Hearing Loss in Asymptomatic and Mild Symptomatic Infants With Congenital CytomegalovirusPediatric Infectious Disease Journal
Erratum to “Application of ChatGPT for automated problem reframing across academic domains” [Computers and EducationComputers and Education: Artificial Intelligence
Application of ChatGPT for automated problem reframing across academic domainsComputers and Education: Artificial Intelligence
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid diseaseNature Communications
Intimate Partner Violence Against WomenJournal of Aggression, Maltreatment and Trauma
T eða ekki t, er það efinn?Læknablaðið

2023

Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular EventsJAMA
Erratum toNeuroRehabilitation
Association of eGFR and mortality with use of a joint modelNephrology, dialysis, transplantation
Large-scale plasma proteomics comparisons through genetics and disease associationsNature
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without auraNature Genetics
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Comparison of medication adherence to different oral anticoagulantsBMJ Open
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticariaCommunications Biology
Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosisBritish Journal of Cancer
Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effectAnnals of the Rheumatic Diseases
Screening for possible hypopituitarism following mild traumatic brain injury: The first all-female study. Who do we need to evaluate further?1NeuroRehabilitation

2022

Warfarin is associated with higher rates of epistaxis compared to direct oral anticoagulants: A nationwide propensity score-weighted studyJournal of internal medicine
Survival, causes of death, and the prognostic role of comorbidities in chronic lymphocytic leukemia in the pre-ibrutinib era: A population-based studyEuropean Journal of Haematology
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology (Nature Communications, (2022), 13, 1, (634), 10.1038/s41467-022-28167-1)Nature Communications
Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint ReplacementsArthritis & rheumatology (Hoboken, N.J.)
Monitoring iron stores in Icelandic blood donors from 1997 through 2019Transfusion Medicine
Incidence of and risk factors of chronic kidney disease: results of a nationwide study in IcelandClinical Kidney Journal
Author CorrectionNature Communications
Multiomics study of nonalcoholic fatty liver diseaseNature Genetics
Warfarin Is Associated With Higher Rates of Upper But Not Lower Gastrointestinal Bleeding Compared with Direct Oral AnticoagulantsClinical Gastroenterology and Hepatology
Prevalence, clinical characteristics and outcomes of hypoxic hepatitis in critically ill patientsScandinavian journal of gastroenterology.
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathologyNature Communications
Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia SubjectsFrontiers in Aging Neuroscience
Comparison of the effectiveness and safety of direct oral anticoagulantsBlood advances
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subsetAnnals of the rheumatic diseases.

2021

The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in IcelandArthritis and Rheumatology
ErratumCell
High-sensitivity troponins in dialysis patientsClinical Kidney Journal
Women and intimate partner violenceScandinavian Journal of Public Health
Genetic variants associated with platelet count are predictive of human disease and physiological markersCommunications Biology
Autoimmune disease is associated with a lower risk of progression in monoclonal gammopathy of undetermined significanceEuropean Journal of Haematology
Increased risk of inflammatory bowel disease among patients treated with rituximab in Iceland from 2001 to 2018Scandinavian Journal of Gastroenterology
Loss-of-function variants in the tumor-suppressor gene PTPN14 confer increased cancer riskCancer Research
Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?American journal of obstetrics & gynecology MFM
When does fetal head rotation occur in spontaneous labor at termAmerican Journal of Obstetrics and Gynecology
Fetal descent in nulliparous women assessed by ultrasoundAmerican Journal of Obstetrics and Gynecology
Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of DementiaJournal of Alzheimer's Disease
Rivaroxaban Is Associated With Higher Rates of Gastrointestinal Bleeding Than Other Direct Oral AnticoagulantsAnnals of Internal Medicine
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptorCommunications Biology
Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and femalesScandinavian Journal of Gastroenterology
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasisCommunications Biology
Predicting the probability of death using proteomicsCommunications Biology
Large-scale integration of the plasma proteome with genetics and diseaseNature Genetics

2020

High Mortality from Major Vascular Trauma in Traffic AccidentsScandinavian Journal of Surgery
Predictors of Gastrin Elevation Following Proton Pump Inhibitor TherapyJournal of Clinical Gastroenterology
Association of glial and neuronal degeneration markers with Alzheimer’s disease cerebrospinal fluid profile and cognitive functionsAlzheimer's Research & Therapy
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid diseaseNature
Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancerBasic and Clinical Pharmacology and Toxicology
Abstinence from alcohol and alcohol rehabilitation therapy in alcoholic liver diseaseScandinavian Journal of Gastroenterology
A nationwide study on hepatocellular carcinomaCancer Epidemiology
Suicide rates in Iceland before and after the 2008 Global RecessionEuropean Journal of Public Health
Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK BiobankCommunications Biology
The prevalence of chronic kidney disease in Iceland according to KDIGO criteria and age-adapted estimated glomerular filtration rate thresholdsKidney International
Increase in the incidence of alcoholic pancreatitis and alcoholic liver disease in Iceland: impact of per capita alcohol consumptionScandinavian Journal of Gastroenterology
Long-term Outcome of Implantable Cardioverter/Defibrillator Lead FailureJAMA Internal Medicine

2019

Biochemical response to ursodeoxycholic acid among PBC patientsScandinavian Journal of Gastroenterology
Parental longevity and survival among patients with multiple myeloma and monoclonal gammopathy of undetermined significanceBritish Journal of Haematology
A pleasant experience of peer evaluation in statistical educationTímarit Kennslumiðstöðvar Háskóla Íslands
Proton pump inhibitor use and risk of breast cancer, prostate cancer, and malignant melanomaPharmacoepidemiology and Drug Safety
The mother’s risk of premature death after child loss across two centurieseLife
Computerized algorithms compared with a nephrologist's diagnosis of acute kidney injury in the emergency departmentEuropean Journal of Internal Medicine
Ara h 1 and Ara h 6 Sensitization Causes Clinical Peanut Allergy in Ara h 2-Negative IndividualsInternational Archives of Allergy and Immunology

2018

The SHA ₂ PE scoreScandinavian Journal of Gastroenterology
The association between different traumatic life events and suicidality.European Journal of Psychotraumatology
Proton-pump inhibitors among adultsTherapeutic Advances in Gastroenterology
Viðhorf íslenskra kvenna til erfðaráðgjafar og erfðaprófa á BRCA1 og BRCA2 stökkbreytingumLæknablaðið
Views of Icelandic women towards genetic counseling - and testing of BRCA2 mutationsLaeknabladid
The association between different traumatic life events and suicidalityEuropean Journal of Psychotraumatology
La asociación de diferentes eventos traumáticos vitales y suicidalidadEuropean Journal of Psychotraumatology
Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based StudyScandinavian Journal of Surgery
Dietary intake is associated with risk of multiple myeloma and its precursor diseasePLoS ONE
The SHA2PE score: a new score for lower gastrointestinal bleeding that predicts low-risk of hospital-based intervention.Scandinavian Journal of Gastroenterology
Physical activity may decrease the likelihood of children developing constipationActa Paediatrica, International Journal of Paediatrics
Variations in elderly peoples’ visits to the emergency departments in IcelandInternational Emergency Nursing

2017

The impact of prior malignancies on second malignancies and survival in MM patientsBlood advances
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERDJournal of Clinical Gastroenterology
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myelomaBlood advances
Regional differences in mortality, hospital discharges and primary care contacts for cardiovascular diseaseScandinavian Journal of Public Health
Reduced anticoagulation variability in patients on warfarin monitored with Fiix-prothrombin time associates with reduced thromboembolismJournal of Thrombosis and Thrombolysis
Editor's Choice- Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromesEuropean heart journal. Acute cardiovascular care
A population-based study on epidemiology of intensive care unit treated traumatic brain injury in IcelandActa Anaesthesiologica Scandinavica
Suicide attempts and self-harm during a dramatic national economic transitionEuropean Journal of Public Health
Greiningarferli lungnakrabbameins á landspítalaLæknablaðið
Fast diagnostic track for suspected lung cancer: A patient centered approachLaeknabladid
Greiningarferli lungnakrabbameins á landspítalaLaeknabladid
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERD A Double-Blind Randomized TrialJournal of Clinical Gastroenterology
History of autoimmune disease is associated with impaired survival in multiple myeloma and monoclonal gammopathy of undetermined significanceAnnals of Hematology
Bone disease in monoclonal gammopathy of undetermined significanceBlood advances

2016

Association between Daily Hydrogen Sulfide Exposure and Incidence of Emergency Hospital Visits: A Population-Based StudyPLoS ONE
Dialysis modality and nutritional status are associated with variability of inflammatory markers.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromesEuropean Heart Journal: Acute Cardiovascular Care
Fiix-prothrombin time monitoring improves warfarin anticoagulation outcome in atrial fibrillationInternational Journal of Laboratory Hematology
Faraldsfræði tveggja Laurén-flokka kirtilfrumukrabbameina í maga á Íslandi árin 1990-2009Læknablaðið
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in childrenActa Paediatrica, International Journal of Paediatrics
Survival in multiple myeloma patients who develop second malignanciesHaematologica
Epidemiology of the two types of gastric adenocarcinoma in Iceland according to the Laurén histological classification 1990-2009,Faraldsfrædi tveggja flokka kirtilfrumukrabbameina í maga á Íslandi samkvæmt vefjaflokkunarkerfi Laurén árin 1990-2009Laeknabladid
The incidence and mortality of acute thoracic aortic dissectionEuropean Journal of Cardio-thoracic Surgery
Improved Survival in AL Amyloidosis: A Population-Based Study on 1,430 Patients Diagnosed in Sweden 1995-2013Blood
Warfarin as a new oral anticoagulant agent?Journal of Thrombosis and Haemostasis
Risk of Progression in Monoclonal Gammopathy of Undetermined Significance (MGUS): Results from a Population-Based Screening StudyBlood
Individualised risk assessment for diabetic retinopathy and optimisation of screening intervalsBritish Journal of Ophthalmology

2015

The role of diagnosis and clinical follow-up of monoclonal gammopathy of undetermined significance on survival in multiple myelomaJAMA Oncology
The effect of SNPs on expression levels in Nimblegen RNA expression microarraysInternational Journal of Data Mining and Bioinformatics
Maternal geographic residence, local health service supply and birth outcomesActa Obstetricia et Gynecologica Scandinavica
Pregnancy-induced hypertensive disorders before and after a national economic collapsePLoS ONE
Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy.Frontline Gastroenterology
Smoking and obesity among pregnant women in Iceland 2001-2010European Journal of Public Health
Fiix-prothrombin time versus standard prothrombin time for monitoring of warfarin anticoagulationThe Lancet Haematology
Survival in patients with familial and sporadic myeloproliferative neoplasmsBlood
Information Technology and Diabetic Eye Screening: Validation, Patient Education, and Economic ImpactDiabetes
Vitamin D and Glucose Regulation in Icelandic Patients with Acute Coronary SyndromeCardiology
Hodgkin lymphoma risk following infectious and chronic inflammatory diseases: a large population-based case-control study from SwedenInternational Journal of Hematology
Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix versus porcine small-intestine submucosa: a noninferiority study.The international journal of lower extremity wounds
Topical dexamethasone γ-cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedemaActa Ophthalmologica
Population-based study on the impact of the familial form of Waldenstrom macroglobulinemia on overall survivalBlood

2014

Long term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver diseaseBMC Gastroenterology
A method for detecting long non-coding RNAs with tiled RNA expression microarraysPLoS ONE
Monitoring Warfarin with the Fiix-Prothrombin Time Improves Anticoagulation Stability and Long-Term Clinical Outcome. the Fiix-TrialBlood
Dorzolamide cyclodextrin nanoparticle suspension eye drops and trusopt in rabbitJournal of Ocular Pharmacology and Therapeutics
Obesity and Risk of Monoclonal Gammopathy of Undetermined Significance: A Population-Based StudyBlood
Patterns of Infectious Morbidity in Patients with Waldenstrom's Macroglobulinaemia/Lymphoplasmacytic Lymphoma: A Population-Based StudyBlood
Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathyDiabetologia
Emergency department visits and revisits by elderly people 2008-2012 in IcelandInternational Emergency Nursing
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluidActa Ophthalmologica

2013

Impact Of History Of Autoimmune Disease On Survival In Multiple Myeloma Monoclonal Gammopathy Of Undetermined Significance: A Population-Based StudyBlood
Multiple Myeloma Patients With Prior Knowledge Of MGUS Have a Better Survival Compared To Multiple Myeloma Patients Without Prior Knowledge Of MGUSBlood
Bone Marrow Fibrosis In Patients With Multiple Myeloma: A New Prognostic Factor For Survival?Blood

2009

Identification and classification of expressed RNA probes in microarray experiments Joint Statistical Meetings (JSM) proceedings, Biometrics Section

Keywords for Specialisation:

Applied statistics