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Thor Aspelund - Professor

Thor Aspelund

–

School of Health Sciences

Thor Aspelund

Professor

Statistician

Location
Sturlugata 8
Phone
7675151 7675151
Email
thor [at] hi.is

Unit
Public Health Sciences

Curriculum Vitae
Thor Aspelund - Curriculum Vitae
ORCID site
https://orcid.org/0000-0002-7998-5433
Research portal – Thor Aspelund

Published works

2024

Worldwide trends in underweight and obesity from 1990 to 2022The Lancet
Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning ApproachHypertension
Plasma proteomic signature of human longevityAging Cell
Long-term survival of 57 premolars consecutively transplanted to premolar sitesAmerican Journal of Orthodontics and Dentofacial Orthopedics
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s diseaseNature Aging
Childhood maltreatment and risk of endocrine diseasesBMC Medicine
History of childhood maltreatment associated with hospitalization or death due to COVID-19BMC Medicine
Correction toNature Aging
Association Between Autoimmune Diseases and Monoclonal Gammopathy of Undetermined SignificanceAnnals of Internal Medicine
Adverse Childhood Experiences and Adult Mental Health OutcomesJAMA Psychiatry
Nocturnal gastro-oesophageal reflux and respiratory symptoms are increased in sleep apnoeaBMJ Open Respiratory Research
Sexual violence in the workplace and associated health outcomesThe Lancet Public Health
Refracture and mortality risk in the elderly with osteoporotic fracturesOsteoporosis International
Mental illness and COVID-19 vaccinationNature Communications
Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined SignificanceAnnals of Internal Medicine
Male-female spatio-temporal differences of age-related bone changes show faster bone deterioration in older women at femoral regions associated with incident hip fractureJournal of Bone and Mineral Research
Prior cancer and risk of monoclonal gammopathy of undetermined significanceHaematologica
Polysomnographic characteristics of excessive daytime sleepiness phenotypes in obstructive sleep apneaSleep

2023

Proteomic prediction of incident heart failure and its main subtypesEuropean Journal of Heart Failure
Exposure factors associated with dementia among older adults in IcelandGeroScience
Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients – an observational study of five cohorts across four countriesThe Lancet Regional Health - Europe
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countriesEClinicalMedicine
Author Correction: Prevalence of smoldering multiple myeloma based on nationwide screeningNature Medicine
Psychobiological stress response to a lung cancer diagnosisActa Oncologica
Diminishing benefits of urban living for children and adolescents’ growth and developmentNature
Prevalence of smoldering multiple myeloma based on nationwide screeningNature Medicine
Mæðradauði á Íslandi 1976-2015Læknablaðið
Proteomic associations with forced expiratory volumeRespiratory Research
Trends in incident diagnoses and drug prescriptions for anxiety and depression during the COVID-19 pandemicTranslational Psychiatry
Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometryBlood Cancer Journal
Psychiatric comorbidities in women with cardiometabolic conditions with and without ADHDBMC Medicine
Trends of perceived disruption in healthcare services during the pandemicEuropean Journal of Public Health
Author Correction: Prevalence of smoldering multiple myeloma based on nationwide screeningNature Medicine
Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countriesThe Lancet Diabetes and Endocrinology
Mental health and sociodemographic characteristics among Icelanders, data from a cross-sectional study in IcelandBMC Psychiatry
COVID-19 illness severity and 2-year prevalence of physical symptomsThe Lancet Regional Health - Europe
Positive airway pressure treatment affects respiratory symptoms and gastro-oesophageal refluxERJ Open Research
Serum DHEA and Testosterone Levels Associate Inversely with Coronary Artery Calcification in Elderly Men
Association between adverse childhood experiences and perinatal depressive symptomsArchives of Women's Mental Health
Twin birth rates and obstetric interventions in IcelandInternational Journal of Gynecology and Obstetrics
Correlates of Coronavirus Disease 2019 Inpatient Mortality at a Southern California Community Hospital With a Predominantly Hispanic/Latino Adult PopulationOpen Forum Infectious Diseases
A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Adverse childhood experiences and psychological functioning among women with schizophrenia or bipolar disorderBritish journal of psychiatry : the journal of mental science
Postpartum pelvic organ prolapse and pelvic floor muscle trainingInternational Urogynecology Journal

2022

Association between adverse childhood experiences and premenstrual disordersBMC Medicine
A genome-wide association study of serum proteins reveals shared loci with common diseasesNature Communications
Adverse childhood experiences and resilience among adult womeneLife
Association between Adverse Childhood Experiences and Multiple Sclerosis in Icelandic Women-A Population-Based Cohort StudyBrain Sciences
The mechanisms by which external school evaluation in Iceland influences internal evaluation and school professionals’ practicesNordic Journal of Studies in Educational Policy
Áhrif menntunar á áhættuþætti og nýgengi æðakölkunarsjúkdómaLæknablaðið
Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study
Mild-to-Moderate Kidney Dysfunction and Cardiovascular DiseaseCirculation
Cerebrovascular Risk-Factors of Prevalent and Incident Brain Infarcts in the General PopulationStroke
APOE epsilon 4 and late-life cognition: mediation by structural brain imaging markersEuropean Journal of Epidemiology
Lifetime exposure to violence and other life stressors and hair cortisol concentration in womenStress
Sleep disturbances among women in a Subarctic region: a nationwide studySleep
A proteogenomic signature of age-related macular degeneration in bloodNature Communications
Different components of excessive daytime sleepiness and the change with positive airway pressure treatment in patients with obstructive sleep apnea: Results from the Icelandic Sleep Apnea Cohort (ISAC)Journal of Sleep Research
Perceived stress and hair cortisol concentration in a study of Mexican and Icelandic womenPLOS Global Public Health
The first wave of COVID-19 and concurrent social restrictions were not associated with a negative impact on mental health and psychiatric well-beingJournal of Internal Medicine
The Proteomic Profile of Interstitial Lung AbnormalitiesAmerican Journal of Respiratory and Critical Care Medicine
Carotid plaque is strongly associated with coronary artery calcium and predicts incident coronary heart disease in a population-based cohortAtherosclerosis
Growth Rate in Childhood and Adolescence and the Risk of Breast and Prostate CancerAmerican Journal of Epidemiology
Heart failure risk is accurately predicted by certain serum proteins
The mechanisms by which external school evaluation in Iceland influences internal evaluation and school professionals’ practicesNordic Journal of Studies in Educational Policy
Risk factors for workplace sexual harassment and violence among a national cohort of women in IcelandThe Lancet Public Health
Cohort ProfileInternational Journal of Epidemiology
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nationsThe Lancet Public Health
Coding and regulatory variants are associated with serum protein levels and diseaseNature Communications
Áhrif menntunar á áhættuþætti og nýgengi æðakölkunarsjúkdómaLæknablaðið

2021

Optimal communication associated with lower risk of acute traumatic stress after lung cancer diagnosisSupportive Care in Cancer
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweighteLife
Optimal communication associated with lower risk of acute traumatic stress after lung cancer diagnosis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Diffuse idiopathic skeletal hyperostosis in elderly Icelanders and its association with the metabolic syndromeScandinavian Journal of Rheumatology
Computed tomography-based skeletal muscle and adipose tissue attenuationExperimental Gerontology
A genome-wide association study of serum proteins reveals shared loci with common diseases
Comorbidities in multiple myeloma and implications on survivalEuropean Journal of Haematology
Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018Læknablaðið
Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018Læknablaðið
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019The Lancet
A genome-wide association study of serum proteins reveals shared loci with common diseases
Randomized Trial for Weight Loss Using a Digital Therapeutic ApplicationJournal of diabetes science and technology
Exploratory assessment of pineal gland volume, composition, and urinary 6-sulfatoxymelatonin levels on prostate cancer riskProstate
Gæði fitu í mataræðinu hefur áhrif á heilsu okkarLæknablaðið
Dietary patterns in adolescence and risk of colorectal cancer: a population-based study.Cancer causes & control : CCC
Cross-sectional study of early postpartum pelvic floor dysfunction and related bother in primiparous women 6–10 weeks postpartumInternational Urogynecology Journal
Dietary patterns in adolescence and risk of colorectal cancerCancer Causes and Control
Accelerated decline in quadriceps area and Timed Up and Go test performance are associated with hip fracture risk in older adults with impaired kidney functionExperimental Gerontology
Serum levels of ACE2 are higher in patients with obesity and diabetesObesity Science and Practice
Untangling fracture risk in monoclonal gammopathy of undetermined significanceEuropean Journal of Haematology
A model for social spreading of Covid-19Physica A: Statistical Mechanics and its Applications
A nationwide study on inpatient opportunistic infections in patients with chronic lymphocytic leukemia in the pre-ibrutinib eraEuropean Journal of Haematology
Illness severity and risk of mental morbidities among patients recovering from COVID-19BMJ Open
Severe volcanic SO₂ exposure and respiratory morbidity in the Icelandic population – a register studyEnvironmental Health: A Global Access Science Source
Increased respiratory morbidity associated with exposure to a mature volcanic plume from a large Icelandic fissure eruptionNature Communications

2020

Coding and regulatory variants affect serum protein levels and common disease
Það sem ég tala um þegar ég tala um COVID-19Læknablaðið
ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19
Antihypertensive medication uses and serum ACE2 levels
Circulating protein signatures and causal candidates for type 2 diabetesDiabetes
The associations of interstitial lung abnormalities with cancer diagnoses and mortalityThe European respiratory journal
The effect of the 2008 recession on well-being and employment status of people with and without mental health problemsEuropean Journal of Public Health
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratioInternational Journal of Epidemiology
Cigarette Smoking Is Associated with Lower Quadriceps Cross-sectional Area and Attenuation in Older AdultsNicotine and Tobacco Research
Fractures and survival in multiple myelomaHaematologica
Association between lung function decline and obstructive sleep apnoea: the ALEC studySleep & breathing = Schlaf & Atmung
A population-based study on serious inpatient bacterial infections in patients with chronic lymphocytic leukemia and their impact on survivalEuropean Journal of Haematology
Quantitative 3D imaging parameters improve prediction of hip osteoarthritis outcomeScientific Reports
Diabetic eye screening with variable screening intervals based on individual risk factors is safe and effective in ophthalmic practiceActa Ophthalmologica
Preterm births in Iceland 1997-2016Birth
Can postpartum pelvic floor muscle training reduce urinary and anal incontinence?American Journal of Obstetrics and Gynecology
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territoriesThe Lancet
Það sem ég tala um þegar ég tala um COVID-19Laeknabladid
Improved brain perfusion after electrical cardioversion of atrial fibrillationEuropace
Repositioning of the global epicentre of non-optimal cholesterolNature
A pooled-analysis of age and sex based coronary artery calcium scores percentilesJournal of Cardiovascular Computed Tomography

2019

Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study.PLoS ONE
Sjálfbært mataræði til bjargarLaeknabladid
Rising rural body-mass index is the main driver of the global obesity epidemic in adultsNature
Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European CohortsNutrients
Snoring and nocturnal reflux: association with lung function decline and respiratory symptomsERJ Open Research
Development and predictors of psychological outcomes following the 2008 earthquake in IcelandScandinavian Journal of Public Health
Severe volcanic SO2 exposure and respiratory morbidities in the Icelandic population – a register study
Tímabundin tannholdsfærsla fyrir máttöku. Slembin, klínísk samanburðarrannsókn á notkun þráða, álklóríð-kvoðu og sambland af aðferðunum tveimurTannlæknablaðið
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik StudyPLoS ONE
Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilunLæknablaðið
Type 2 diabetes and obesity in midlife and breast cancer risk in the Reykjavik cohortCancer Causes and Control
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processingNature Genetics
Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European CohortsNutrients
Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilunLæknablaðið
Author CorrectionNature Genetics
Sjálfbært mataræði til bjargarLæknablaðið
Hand and knee osteoarthritis are associated with reduced diameters in retinal vesselsRheumatology International
Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep-related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological studyJournal of Sleep Research
Effects of cardiac rehabilitation on the physical capacity of individuals with heart failureLæknablaðið
Pre-diagnostic 25-hydroxyvitamin D levels and survival in cancer patientsCancer Causes and Control
Biofidelic finite element models for accurately classifying hip fracture in a retrospective clinical study of elderly women from the AGES Reykjavik cohortBone
Do female elite athletes experience more complicated childbirth than non-athletes? A case-control studyBritish Journal of Sports Medicine
Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanismsAlzheimer's and Dementia
Body fat distribution on computed tomography imaging and prostate cancer risk and mortality in the AGES-Reykjavik studyCancer
Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adultsEuropean Heart Journal
Respiratory health among professionals exposed to extreme SO<inf>2</inf> levels from a volcanic eruptionScandinavian Journal of Work, Environment and Health
Respiratory health among professionals exposed to extreme SO₂ levels from a volcanic eruptionScandinavian Journal of Work, Environment and Health

2018

Preeclampsia and academic performance in children: A nationwide study from IcelandPLoS ONE
Co-regulatory networks of human serum proteins link genetics to diseaseScience
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participantsInternational Journal of Epidemiology
Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusionEuropace
Fracture strength of zirconia implant abutments on narrow diameter implants with internal and external implant abutment connectionsClinical Oral Implants Research
Long-term survival of patients with acute myocardial infarction in Iceland,Langtímahorfur sjúklinga með bráða kransæðastífluLaeknabladid
Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø studyBMJ Open
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's diseaseAlzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
Predictors of carotid plaque progression over a 4-year follow-up in the Reykjavik REFINE-studyAtherosclerosis
Midlife metabolic factors and prostate cancer risk in later lifeInternational Journal of Cancer
Nationwide study highlights a second peak in ACL tears for women in their early fortiesKnee Surgery, Sports Traumatology, Arthroscopy
A multicenter randomized, controlled clinical trial comparing the use of displacement cords, an aluminum chloride paste, and a combination of paste and cords for tissue displacementJournal of Prosthetic Dentistry
The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomyScandinavian Journal of Gastroenterology
Accidental injuries among older adultsInternational Emergency Nursing
Predictors of women's positive childbirth pain experienceWomen and Birth
Sex differences in the spatial distribution of bone in relation to incident hip fractureBone
Interstitial lung abnormalities and physical functionERJ Open Research
Cigarette smoking and hip volumetric bone mineral density and cortical volume loss in older adultsBone
Associations between Proportion of Plasma Phospholipid Fatty Acids, Depressive Symptoms and Major Depressive Disorder. Cross-Sectional Analyses from the AGES Reykjavik StudyJournal of Nutrition, Health and Aging
CorrectionPLoS ONE
Langtímahorfur sjúklinga með bráða kransæðastífluLæknablaðið
Interstitial lung abnormalities and self-reported health and functional statusThorax
Midlife metabolic factors and prostate cancer risk in later lifeInternational Journal of Cancer
Dietary habits in adolescence and midlife and risk of breast cancer in older womenPLoS ONE
Cigarette smoking and hip volumetric bone mineral density and cortical volume loss in older adults: The AGES-Reykjavik studyBone
Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø studyBMJ Open
Langtímahorfur sjúklinga með bráða kransæðastífluLæknablaðið
Association of Unrecognized Myocardial Infarction with Long-term Outcomes in Community-Dwelling Older AdultsJAMA Cardiology
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studiesEuropean Heart Journal
Dietary habits in adolescence and midlife and risk of breast cancer in older womenPLoS ONE

2017

Greiningarferli lungnakrabbameins á Landspítala: sjúklingamiðuð nálgunLæknablaðið
Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndromePLoS ONE
Fibrosis as measured by the biomarker, tissue inhibitor metalloproteinase-1, predicts mortality in Age Gene Environment Susceptibility-Reykjavik (AGES-Reykjavik) StudyEuropean Heart Journal
Prevalence of heart failure in the elderly and future projectionsScandinavian Cardiovascular Journal
Hjartabilun meðal eldri ÍslendingaLaeknabladid
Early life residence, fish consumption, and risk of breast cancerCancer Epidemiology Biomarkers and Prevention
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkersHeart
Fast diagnostic track for suspected lung cancer: A patient centered approachLaeknabladid
Úr gögnum HjartaverndarLaeknabladid
Proximal Femur Volumetric Bone Mineral Density and MortalityJournal of Bone and Mineral Research
Causal effect of plasminogen activator inhibitor type 1 on coronary heart diseaseJournal of the American Heart Association
Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortiumPLoS ONE
Greiningarferli lungnakrabbameins á landspítalaLaeknabladid
Samsvörun milli heildarmagns tannátu meðal 12 og 15 ára barna (DMFT/DMFS) og tannátu í lykiltönnumTannlæknablaðið
Úr gögnum Hjartaverndar: Nokkur atriði um faraldsfræði og áhættumat beinbrota á ÍslandiLæknablaðið
Úr gögnum Hjartaverndar: Faraldsfræði kransæðasjúkdóma á Íslandi í hálfa öldLæknablaðið
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypesEuropean Respiratory Journal
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney functionScientific Reports
Hjartabilun meðal eldri Íslendinga. Algengi, nýgengi, undirliggjandi sjúkdómar og langtímalifunLæknablaðið
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass indexMolecular Psychiatry
Greiningarferli lungnakrabbameins á landspítalaLæknablaðið
CorrigendumScientific Reports
Endothelial Function Assessed by Peripheral Arterial Tonometry is not related to Cardiovascular Risk Score in Healthy SubjectsInternational Cardiovascular Forum
Staðbundin notkun metronidazole við tannhaldsskurðmeðferð á jöxlum með millirótabólguTannlæknablaðið
Long-Term Hormone Replacement Therapy Is Associated with Low Coronary Artery Calcium Levels in a Cohort of Older WomenJournal of the American Geriatrics Society
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypesEuropean Respiratory Journal
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016The Lancet
Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General PopulationStroke
[Fast diagnostic track for suspected lung cancer: A patient centered approach]Læknablaðið
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's diseaseNature Genetics
Úr gögnum HjartaverndarLaeknabladid
Associations of 24-hour sleep duration and CT-derived measurements of muscle and boneExperimental Gerontology
Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndrome.PLoS ONE
Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General PopulationStroke
Greiningarferli lungnakrabbameins á landspítalaLaeknabladid

2016

Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older womenPublic Health Nutrition
Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individualsAlzheimer's and Dementia
Total population-based study of the impact of substance use disorders on the overall survival of psychiatric inpatientsNordic Journal of Psychiatry
Mental disorder, imprisonment and reduced life expectancy - A nationwide psychiatric inpatient cohort studyCriminal Behaviour and Mental Health
Obstetric outcomes of mothers previously exposed to sexual violencePLoS ONE
Exploring potential mortality reductions in 9 European countries by improving diet and lifestyleInternational Journal of Cardiology
Occupation as a risk factor for renal cell cancerScandinavian Journal of Urology
Favorable Survival after Aortic Valve Replacement Compared to the General PopulationThe Journal of heart valve disease
Blood donors in IcelandTransfusion
Incidence and prevalence of total joint replacements due to osteoarthritis in the elderlyBMC Musculoskeletal Disorders
Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and womenOsteoporosis International
Midlife cardiovascular risk factors and late-life unrecognized and recognized myocardial infarction detect by cardiac magnetic resonanceJournal of the American Heart Association
Natriuretic peptides and integrated risk assessment for cardiovascular diseaseThe Lancet Diabetes and Endocrinology
High-sensitivity cardiac troponin i is a strong predictor of cardiovascular events and mortality in the ages-reykjavik community-based cohort of older individualsClinical Chemistry
Prevalence and prognosis of non-ischemic patterns of late gadolinium enhancement in older adults by cardiovascular MR in the Iceland-MI studyJournal of Cardiovascular Magnetic Resonance
Individualised risk assessment for diabetic retinopathy and optimisation of screening intervalsBritish Journal of Ophthalmology
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in DiabetesDiabetes
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney functionNature Communications
Post-stroke bacteriuria among stroke patients attending a physiotherapy clinic in Ghana: a cross-sectional studyTherapeutics and Clinical Risk Management
Association between interstitial lung abnormalities and all-cause mortalityJAMA - Journal of the American Medical Association
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's DiseasePLoS Genetics
ErratumInternational Journal of Cardiology
Association of Forced Vital Capacity with the Developmental Gene NCOR2PLoS ONE
The association between midlife physical activity and depressive symptoms in late lifeJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Cerebrovascular Damage Mediates Relations Between Aortic Stiffness and MemoryHypertension
Pineal gland volume assessed by MRI and its correlation with 6-sulfatoxymelatonin levels among older menJournal of Biological Rhythms
Association of cancer incidence and duration of residence in geothermal heating area in IcelandPLoS ONE
Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik studyBMJ Open
Airflow obstruction, atherosclerosis and cardiovascular risk factors in the AGES Reykjavik studyAtherosclerosis

2015

Quality Pain Management Practices in a University HospitalPain Management Nursing
Segmental kidney volumes measured by dynamic contrast-enhanced magnetic resonance imaging and their association with CKD in older peopleAmerican Journal of Kidney Diseases
A blunted diurnal cortisol response in the lower educated does not explain educational differences in coronary heart diseaseSocial Science and Medicine
Quality Pain Management in the Hospital Setting from the Patient's PerspectivePain Practice
Overweight and obesity in midlife and brain structure and dementia 26 years laterAmerican Journal of Epidemiology
PLD3 variants in population studiesNature
Midlife Blood Pressure and Late-Life GFR and AlbuminuriaAmerican Journal of Kidney Diseases
Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adultsJournal of Nutrition
Physical activity from early adulthood and risk of prostate cancerCancer Prevention Research
Covariate-adjusted measures of discrimination for survival dataBiometrical Journal
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacyJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive proteinPLoS ONE
Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density lociPLoS ONE
A total population-based cohort study of female psychiatric inpatients who have served a prison sentenceCriminal Behaviour and Mental Health
Relations between aortic stiffness and left ventricular structure and function in older participants in the age, gene/environment susceptibility-reykjavik studyCirculation: Cardiovascular Imaging
Feasibility of Using Pseudo-Continuous Arterial Spin Labeling Perfusion in a Geriatric Population at 1.5 TeslaPLoS ONE
Genome-wide association study of kidney function decline in individuals of European descentKidney International
Mediation analysis of aortic stiffness and renal microvascular functionJournal of the American Society of Nephrology
Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adultsAmerican Journal of Clinical Nutrition
Carotid atherosclerosis and cardiovascular health metrics in old subjects from the AGES-Reykjavik studyAtherosclerosis
Information Technology and Diabetic Eye Screening: Validation, Patient Education, and Economic ImpactDiabetes
Lifetime risk of stage 3–5 CKD in a community-based sample in IcelandClinical Journal of the American Society of Nephrology
Urinary melatonin levels, sleep disruption, and risk of prostate cancer in elderly menEuropean Urology
A Meta-analysis of Gene Expression Signatures of Blood Pressure and HypertensionPLoS Genetics
Fat distribution and mortalityObesity

2014

Longitudinal and circumferential strain of the proximal aortaJournal of the American Heart Association
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation riskEuropace
Community awareness of stroke in Accra, GhanaBMC Public Health
The relationship between chronic pain pattern, interference with life and health-related quality of life in a nationwide community samplePain Management Nursing
The alcohol paradoxJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Joint effect of mid- and late-life blood pressure on the brainNeurology
Genetic determinants of heel bone propertiesHuman Molecular Genetics
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortalityNutrition, Metabolism and Cardiovascular Diseases
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male pubertyHuman Molecular Genetics
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAXOsteoporosis International
ErratumOsteoporosis International
Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathyDiabetologia
Longitudinal changes in size and composition of carotid artery plaques using ultrasoundJournal for Vascular Ultrasound
Population assessment of future trajectories in coronary heart disease mortalityPLoS ONE
Spousal loss and cognitive function in later lifeAmerican Journal of Epidemiology
Risk factors and health during pregnancy among women previously exposed to sexual violenceActa Obstetricia et Gynecologica Scandinavica
Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008Osteoporosis International
Pulse pressure relation to aortic and left ventricular structure in the age, gene/environment susceptibility (AGES)-reykjavik studyHypertension
Assessment of incident spine and hip fractures in women and men using finite element analysis of CT scansJournal of Bone and Mineral Research
Genome-wide association analysis identifies six new loci associated with forced vital capacityNature Genetics
Assessing risk prediction models using individual participant data from multiple studiesAmerican Journal of Epidemiology
The prevalence of aortic stenosis in the elderly in Iceland and predictions for the coming decadesInternational Journal of Cardiology
Profile and health-related quality of life of Ghanaian stroke survivorsClinical Interventions in Aging

2013

Socioeconomic factors from midlife predict mobility limitation and depressed mood three decades later; findings from the AGES-Reykjavik Study.BMC Public Health
Áhrif 6 mánaða fjölþættrarþjálfunar á hreyfigetu, vöðvakraft, þol og líkamsþyngdarstuðul eldri einstaklinga. Eru áhrif þjálfunar sambærileg hjá konum og körlum?Læknabladid
Hemostatic Factors and Risk of Coronary Heart Disease in General PopulationsPLoS ONE
Type 3 finger length pattern is associated with total knee replacements due to osteoarthritis but not with hip replacements or hand osteoarthritis in the elderlyBMC Musculoskeletal Disorders
The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetesPLoS ONE
Similar decline in mortality rate of older persons with and without type 2 diabetes between 1993 and 2004 the Icelandic population-based Reykjavik and AGES-Reykjavik cohort studiesBMC Public Health
Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse populationJournal of the American Heart Association
Insights into the Genetic Architecture of Early Stage Age-Related Macular DegenerationPLoS ONE
Pulmonary function impairment may be an early risk factor for late-life cognitive impairmentJournal of the American Geriatrics Society
Coronary artery calcium and physical performance as determinants of mortality in older ageInternational Journal of Cardiology
Prevalence of airflow obstruction in nonsmoking older individuals using different spirometric criteriaCOPD: Journal of Chronic Obstructive Pulmonary Disease
Migraine, depression, and brain volumeNeurology
Genetic associations with valvular calcification and aortic stenosisNew England Journal of Medicine
Similarities and differences between sexes in regional loss of cortical and trabecular bone in the mid-femoral neckJournal of Bone and Mineral Research
Changes in total cholesterol levels in Western societies are not related to statin, but rather dietary factorsEuropean Heart Journal
Genetic Loci for Retinal Arteriolar MicrocirculationPLoS ONE
ErratumEuropean Heart Journal
CRP is associated with lung function decline in men but not womenRespiratory Medicine
Early peak height velocity and cardiovascular disease mortality among Icelandic womenAnnals of Medicine
Common variants in mendelian kidney disease genes and their association with renal functionJournal of the American Society of Nephrology
Persistence of the effect of birth size on dysglycaemia and type 2 diabetes in old ageAge
Atrial fibrillation is associated with reduced brain volume and cognitive function independent of cerebral infarctsStroke
Midlife physical activity preserves lower extremity function in older adultsJournal of the American Geriatrics Society
Causal Relationship between Obesity and Vitamin D StatusPLoS Medicine
Effects of exercise training and nutrition counseling on body composition and cardiometabolic factors in old individualsEuropean Geriatric Medicine
Consumption of Fish Products across the Lifespan and Prostate Cancer RiskPLoS ONE
Genetic loci for retinal arteriolar microcirculation.PLoS ONE
Derivation and assessment of risk prediction models using case-cohort dataBMC Medical Research Methodology

2012

Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik studyAge and Ageing
The use of digital photographs for the diagnosis of hand osteoarthritisBMC Musculoskeletal Disorders
Brain tissue volumes in the general population of the elderly: the AGES-Reykjavik study.NeuroImage
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathwaysNature Genetics
Early life residency associated with the risk of developing type 2 diabetes - The population-based Reykjavík Study.Læknablaðið
Brain tissue volumes by APOE genotype and leisure activity-the AGES-Reykjavik StudyNeurobiology of Aging
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistanceNature Genetics
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney functionHuman Molecular Genetics
Adult height and the risk of cause-specific death and vascular morbidity in 1 million peopleInternational Journal of Epidemiology
Rannsókn á áhættuþáttum hjarta- og æðasjúkdóma hjá geðklofasjúklingum á geðsviði LandspítalaLæknablaðið
Tengsl búsetu fyrstu 20 æviárin við áhættu á sykursýki af tegund 2Laeknabladid
Rannsókn á áhættupáttum hjarta- og æopasjúkdóma hjá geoklofasjúklingum á geosvioi landspítalaLaeknabladid
Rye bread consumption in early life and reduced risk of advanced prostate cancerCancer Causes and Control
Effects of a 6-month multimodal training intervention on retention of functional fitness in older adultsInternational Journal of Behavioral Nutrition and Physical Activity
Coronary artery calcium distributions in older persons in the AGES-reykjavik studyEuropean Journal of Epidemiology
Retinopathy in old persons with and without diabetes mellitusDiabetologia
Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation MeasurementsPLoS ONE
Effect of Birth Year on Birth Weight and Obesity in AdulthoodPLoS ONE
Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adultsJAMA - Journal of the American Medical Association
Brain tissue volumes in the general population of the elderly. The AGES-Reykjavik Study.NeuroImage
Milk intake in early life and risk of advanced prostate cancerAmerican Journal of Epidemiology
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureNature Genetics
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney FunctionPLoS Genetics
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populationsNature Genetics
Common genetic variation in the 3β-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk the aortagen consortiumCirculation: Cardiovascular Genetics
C-reactive protein, fibrinogen, and cardiovascular disease predictionNew England Journal of Medicine
Mid-thigh cortical bone structural parameters, muscle mass and strength, and association with lower limb fractures in older men and women (AGES-Reykjavik Study)Calcified Tissue International

2011

Hand osteoarthritis severity is associated with total knee joint replacements independently of BMI : the Ages-Reykjavik studyOpen Rheumatology Journal
Hand osteoarthritis severity is associated with total knee joint replacements independently of BMI. The Ages-Reykjavik studyOpen Rheumatology Journal
Personalized Epigenomic Signatures That Are Stable over Time and Covary with Body Mass Index (Science Translational Medicine (2011) 3, (65er1))Science Translational Medicine
Genome-wide association studies of cerebral white matter lesion burdenAnnals of Neurology
Trends in the incidence and prevalence of atrial fibrillation in Iceland with future projectionsEuropace
Childhood growth and adult hypertension in a population of high birth weightHypertension
Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik StudyBMJ Open
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traitsPLoS Genetics
The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in womenAnnals of the Rheumatic Diseases
Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projectionsEuropace
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetesDiabetes
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levelsCirculation
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressureNature Genetics
Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathyDiabetologia
CUBN is a gene locus for albuminuriaJournal of the American Society of Nephrology
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarctionCirculation
ErratumNature Genetics
Genetic variants in novel pathways influence blood pressure and cardiovascular disease riskNature
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung functionNature Genetics
Distribution of cortical bone in the femoral neck and hip fractureBone
Meðferð sykursýki tegund 1 með insúlíndælu hjá fullorðnum á ÍslandLæknablaðið
Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility--Reykjavik study.Brain : a journal of neurology
Arterial stiffness, pressure and flow pulsatility and brain structure and functionBrain
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaqueNature Genetics
Meofero sykursýki af tegund 1 meo insúlíndælu hjá fulloronum á ÍslandiLaeknabladid

2010

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conductionNature Genetics
Lonliness of Older Persons in Home Care in IcelandME-JAA Middle East Journal of Age and Ageing
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factorsCirculation: Cardiovascular Genetics
A Meta-analysis of four genome-wide association studies of survival to age 90 years or olderJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six loci influencing serum magnesium levelsPLoS Genetics
Validation of an atrial fibrillation risk algorithm in Whites and African AmericansArchives of Internal Medicine
Genome-wide association study of PR intervalNature Genetics
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular diseaseThe Lancet
Effect of rheumatoid factor on mortality and coronary heart diseaseAnnals of the Rheumatic Diseases
Migraine with aura and risk of cardiovascular and all cause mortality in men and womenBMJ (Online)
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studiesLancet
Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung functionBMC Pulmonary Medicine
New loci associated with kidney function and chronic kidney diseaseNature Genetics
Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivoPLoS Genetics
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexNature Genetics
Correlation of echocardiographic findings with cerebral infarction in elderly adultsStroke
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distributionNature Genetics
Personalized epigenomic signatures that are stable over time and covary with body mass indexScience Translational Medicine
Genome-wide analysis of genetic loci associated with Alzheimer diseaseJAMA - Journal of the American Medical Association
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortalityThe Lancet
Analysing the large decline in coronary heart disease mortality in the icelandic population aged 25-74 between the years 1981 and 2006PLoS ONE
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studiesNature Genetics
Genome-wide association studies of mri-defined brain infarctsStroke
The effect of midlife physical activity on cognitive function among older adultsJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortalityBMJ (Online)
Triglyceride-mediated pathways and coronary diseaseThe Lancet
Markers of dysglycaemia and risk of coronary heart disease in people without diabetesPLoS Medicine
Hundreds of variants clustered in genomic loci and biological pathways affect human heightNature

2009

Migraine headache in middle age and late-life brain infarctsObstetrical and Gynecological Survey
High hand joint mobility is associated with radiological CMC1 osteoarthritisOsteoarthritis and Cartilage
The interaction of adiposity with the CRP gene affects CRP levelsInternational Journal of Obesity
Hand osteoarthritis in older women is associated with carotid and coronary atherosclerosisAnnals of the Rheumatic Diseases
Abnormal T-wave axis is associated with coronary artery calcification in older adultsScandinavian Cardiovascular Journal
Multiple loci influence erythrocyte phenotypes in the CHARGE ConsortiumNature Genetics
Unfavourable risk factors for type 2 diabetes mellitus are already apparent more than a decade before onset in a population-based study of older personsEuropean Journal of Epidemiology
NRXN3Is a novel locus for waist circumferencePLoS Genetics
Þróun holdafars og sykursýki í 40 ár á íslandiLaeknabladid
Migraine headache in middle age and late-life brain infarctsJAMA - Journal of the American Medical Association
Meta-analysis of genome-wide association data identifies two loci influencing age at menarcheNature Genetics
Variants in ZFHX3 are associated with a trial fibrillation in individuals of European ancestryNature Genetics
Genome-wide association study of blood pressure and hypertensionNature Genetics
Genome-wide association meta-analysis for total serum bilirubin levelsHuman Molecular Genetics
C-reactive protein in migraine sufferers similar to that of non-migraineursCephalalgia

2008

Intra-individual change over time in DNA methylation with familial clusteringJAMA - Journal of the American Medical Association
Hemodynamics of increased pulse pressure in older women in the community-based age, gene/environment susceptibility-Reykjavik studyHypertension
Cerebral microbleeds in the population based AGES-Reykjavik studyJournal of Neurology, Neurosurgery and Psychiatry

2007

Algengi sykursýki af tegund tvö á Islandi 1967-2002.Læknabladid
Forspárgildi QRS útslaga á hjartalínuriti, Minnesota-líkanid, un dánartídni karla. Reykjavíkurrannsókn Hjartaverndar.Læknabladid
Clinical features in secondary and cryptogenic organising pneumoniaInternational Journal of Tuberculosis and Lung Disease
Age, gene/environment susceptibility-reykjavik studyAmerican Journal of Epidemiology
Inaccuracy in self-report of fractures may underestimate association with health outcomes when compared with medical record based fracture registryEuropean Journal of Epidemiology
Infant feeding patterns and midlife erythrocyte sedimentation rateActa Paediatrica, International Journal of Paediatrics
Optimum expression of adult lung function based on all-cause mortalityRespiratory Medicine
Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation projectEuropean Journal of Preventive Cardiology
Increasing glucose levels and BMI predict future heart failure. Experience from the Reykjavík StudyEuropean Journal of Heart Failure

2006

Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanismsAtherosclerosis
Skaðleg áhrif reykinga á heilsufar hafa verið verulega vanmetin. Niðurstöður úr hóprannsóknum HjartaverndarLæknabladid
Increasing sex difference in bone strength in old ageBone
Examination of genetic effects of polymorphisms in the MCP-1 and CCR2 genes on MI in the Icelandic populationAtherosclerosis
Epidemiology of organising pneumonia in IcelandThorax

2005

Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced riskJournal of Experimental Medicine
The association between glucose abnormalities and heart failure in the population-based Reykjavík StudyDiabetes Care
Mótefnatengd sykursýki af tegund 2 á IslandiLæknabladid
Glucose abnormalities and heart failure predict poor prognosis in the population-based Reykjavík StudyEuropean Journal of Cardiovascular Prevention and Rehabilitation
Prevalence of chronic kidney disease based on estimated glomerular filtration rate and proteinuria in Icelandic adultsNephrology Dialysis Transplantation

2004

Mótefnatengd sykursýki af tegund 2 á Íslandi: algengi, svipgerð og skyldleiki einstaklinga.Læknablaðið
Vistunarmat aldraðra á árunum 1992-2001 : tengsl við lifun og vistunLæknablaðið
Birtingarmynd heilabilunar í vistunarmati aldraðra fyrir hjúkrunarrými 1992-2001Læknablaðið

2003

Population-based assessment of burn injury in southern IowaJournal of Burn Care and Rehabilitation

2001

Binormal association-marginal models for empirically evaluating and comparing diagnosticsStatistical Modeling

2000

Nýgengi krabbameina meðal verkakvennaLæknablaðið

1997

Occupational risk factors for breast cancer among nursesInternational Journal of Occupational and Environmental Health
A model for estimating meal frequency and meal size from stomach data with an application to Atlantic cod (Gadus morhua) feeding on capelin (Mallotus villosus)Canadian Journal of Fisheries and Aquatic Sciences

1995

Cancer incidence among female manual workersEpidemiology

Keywords for Specialisation:

Applied statistics for biology and health

Survival analysis

Logistic regression

Repeated measures analysis

R statistical program

Clinical Prediction Models