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Jóna Freysdóttir - Professor

Jóna Freysdóttir

–

School of Health Sciences

Jóna Freysdóttir

Professor

Phone
5436852 8612056
Email
jf [at] hi.is

Unit
Faculty of Medicine
Website
http://lifvisindi.hi.is/staff/jona-freysdottir

Published works

2023

Geobarrettin D, a Rare Herbipoline-Containing 6-Bromoindole Alkaloid from Geodia barrettiMolecules

2022

Absorption of colostral immunoglobulin G by Icelandic dairy calvesIcelandic Agricultural Sciences
Dietary Fish Oil Increases the Number of CD11b⁺CD27⁻ NK Cells at the Inflammatory Site and Enhances Key Hallmarks of Resolution of Murine Antigen-Induced PeritonitisJournal of Inflammation Research
Dietary Fish Oil Increases the Number of CD11bCD27 NK Cells at the Inflammatory Site and Enhances Key Hallmarks of Resolution of Murine Antigen-Induced Peritonitis.Journal of Inflammation Research

2021

Keratinocytes secrete multiple inflammatory and immune biomarkers, which are regulated by LL-37, in a psoriasis mimicking microenvironmentScandinavian Journal of Immunology
Seaweed extract improves carbohydrate metabolism in overweight and obese adultsCurrent Nutrition and Food Science
Seaweed extract improves carbohydrate metabolism in overweight and obese adultsCurrent Nutrition and Food Science
Emu Oil and Saireito in combination reduce tumour development and clinical indicators of disease in a mouse model of colitis-associated colorectal cancerBiomedicine and Pharmacotherapy
Keratinocytes secrete multiple inflammatory and immune biomarkers, which are regulated by LL‐37, in a psoriasis mimicking microenvironmentScandinavian Journal of Immunology

2020

Bromotryptamine and Imidazole Alkaloids with Anti-inflammatory Activity from the Bryozoan <i>Flustra foliacea</i>Journal of Natural Products
Docosahexaenoic Acid Modulates NK Cell Effects on Neutrophils and Their CrosstalkFrontiers in Immunology
Anti-inflammatory and proresolving effects of the omega-6 polyunsaturated fatty acid adrenic acidJournal of Immunology
Bromotryptamine and Imidazole Alkaloids with Anti-inflammatory Activity from the Bryozoan Flustra foliaceaJournal of Natural Products

2019

Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells.Free Radical Biology and Medicine
Effective treatment with balneophototherapy and narrowband UVB monotherapy reduces skin homing Th17/Tc17 and Th22/Tc22 effector cells in peripheral blood in patients with psoriasisJournal of Dermatological Science
Exopolysaccharides from Cyanobacterium aponinum induce a regulatory dendritic cell phenotype and inhibit SYK and CLEC7A expression in dendritic cells, T cells and keratinocytesInternational Immunopharmacology
Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cellsFree Radical Biology and Medicine

2018

6-Bromoindole Derivatives from the Icelandic Marine Sponge <em>Geodia barretti</em>: Isolation and Anti-Inflammatory ActivityMarine Drugs
Natural killer cells play an essential role in resolution of antigen-induced inflammation in miceMolecular Immunology
6-Bromoindole Derivatives from the Icelandic Marine Sponge Geodia barretti: Isolation and Anti-Inflammatory ActivityMarine Drugs
6-Bromoindole Derivatives from the Icelandic Marine Sponge : Isolation and Anti-Inflammatory Activity.Marine Drugs

2017

Lipophilic fractions from the marine sponge halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4⁺ T cellsPharmaceutical Biology

2016

Immunomodulatory N-acyl Dopamine Glycosides from the Icelandic Marine Sponge Myxilla incrustans Collected at a Hydrothermal Vent SitePlanta Medica
Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in miceGlycoconjugate Journal
A polysaccharide fraction from Achillea millefolium increases cytokine secretion and reduces activation of Akt, ERK and NF-κB in THP-1 monocytesCarbohydrate Polymers

2015

Differential mobility separation of leukotrienes and protectinsAnalytical Chemistry
Effect of in vitro digested cod liver oil of different quality on oxidative, proteomic and inflammatory responses in the yeast Saccharomyces cerevisiae and human monocyte-derived dendritic cellsJournal of the Science of Food and Agriculture
Exopolysaccharides from Cyanobacterium aponinum from the Blue Lagoon in Iceland increase IL-10 secretion by human dendritic cells and their ability to reduce the IL-17⁺RORγt⁺/IL-10⁺FoxP3⁺ ratio in CD4⁺ T cellsImmunology Letters
Dendritic cells matured in the presence of the lycopodium alkaloid annotine direct T cell responses towards a Th2/Treg phenotype.Phytomedicine
Dendritic cells matured in the presence of the lycopodium alkaloid annotine direct T cell responses toward a Th2/Treg phenotypePhytomedicine

2014

Oxidative processes during enzymatic hydrolysis of cod protein and their influence on antioxidant and immunomodulating abilityFood Chemistry
Polysaccharides from the cyanobacteria Nostoc commune decreases secretion of inflammatory cytokines by THP-1 monocytes and phosphorylation of MAP kinase and Akt/PKB.Phytomedicine
A heteroglycan from the cyanobacterium Nostoc commune modulates LPS-induced inflammatory cytokine secretion by THP-1 monocytes through phosphorylation of ERK1/2 and AktPhytomedicine
Murine antigen-induced inflammation-A model for studying induction, resolution and the adaptive phase of inflammationJournal of Immunological Methods
Welcome to the 42nd Annual Meeting of the Scandinavian Society for Immunology in Reykjavik, IcelandScandinavian Journal of Immunology
Oxidative processes during enzymatic hydrolysis of cod protein and their influence on antioxidant and immunomodulating ability.Food Chemistry
The suppressive function of human CD8⁺ itregs is inhibited by IL-1β and TNFαScandinavian Journal of Immunology
Dietary omega-3 fatty acids enhance the B1 but not the B2 cell immune response in mice with antigen-induced peritonitisJournal of Nutritional Biochemistry

2013

Alkaloids from Galipea longiflora Krause modify the maturation of human dendritic cells and their ability to stimulate allogeneic CD4⁺ T cellsInternational Immunopharmacology
Sulphated polysaccharide from the sea cucumber Cucumaria frondosa affect maturation of human dendritic cells and their activation of allogeneic CD4(+) T cells in vitroBioactive Carbohydrates and Dietary Fibre
Biodiversity of benthic invertebrates and bioprospecting in Icelandic watersPhytochemistry Reviews
Biodiversity of benthic invertebrates and bioprospecting in Icelandic watersPhytochemistry Reviews
Dietary fish oil reduces the acute inflammatory response and enhances resolution of antigen-induced peritonitisJournal of Nutritional Biochemistry
Dietary fish oil increases the proportion of a specific neutrophil subpopulation in blood and total neutrophils in peritoneum of mice following endotoxin-induced inflammationJournal of Nutritional Biochemistry
Quinolinic Alkaloids from Galipea longiflora Krause Suppress Production of Proinflammatory Cytokines in vitro and Control Inflammation in vivo upon Leishmania Infection in MiceScandinavian Journal of Immunology

2012

Two circulating neutrophil populations in acute inflammation in miceInflammation Research
Dietary fish oil decreases the proportion of classical monocytes in blood in healthy mice but increases their proportion upon induction of inflammationJournal of Nutrition

2011

Ethanol extract from birch bark (Betula pubescens) suppresses human dendritic cell mediated Th1 responses and directs it towards a Th17 regulatory response in vitroImmunology Letters
Aqueous extracts from Menyanthes trifoliate and Achillea millefolium affect maturation of human dendritic cells and their activation of allogeneic CD4+ T cells in vitroJournal of Ethnopharmacology
Aqueous extracts from Menyanthes trifoliate and Achillea millefolium affect maturation of human dendritic cells and their activation of allogeneic CD4 ⁺ T cells in vitroJournal of Ethnopharmacology

2010

Immunomodulating effects of extracts from Icelandic marine invertebratesPlanta Medica

2009

Vβ usage and T regulatory cells in children following partial or total thymectomy after open heart surgery in infancyScandinavian Journal of Immunology

2008

In vitro and in vivo immunomodulating effects of traditionally prepared extract and purified compounds from Cetraria islandicaInternational Immunopharmacology
In vitro and in vivo immunomodulating effects of traditonally prepared extracts and purified compounds from Cetraria islandica.International Immunopharmacology
Orofacial granulomatosis: review on aetiology and pathogenesis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Do non-steroidal anti-inflammatory drugs influence chronic inflammation? The effects of piroxicam on chronic antigen-induced arthritis in ratsScandinavian Journal of Rheumatology
In vitro and in vivo immunomodulating effects of traditionally-prepared extract and purified compounds from Cetraria islandicaProceedings of the Nutrition Society

2007

Mucosal tolerance to KLH reduces BSA-induced arthritis in rats - An indication of bystander suppressionJournal of Clinical Immunology
Th1 environment is predominant in oral Crohn’s diseaseInflammatory Bowel Diseases
Oral biopsies from patients with orofacial granulomatosis with histology resembling Crohn's disease have a prominent Th1 environment.Inflammatory Bowel Diseases
Immunomodulating polysaccharides from the lichen Thamnolia vermicularis var. subuliformisPhytomedicine

2006

Diversity of γδ T cells in patients with Behcet’s disease is indicative of polyclonal activation.Oral Diseases
Evidence for extrathymic T cell maturation after thymectomy in infancyClinical and Experimental Immunology
Immunomodulating effects of lichen-derived polysaccharides on monocyte-derived dendritic cellsInternational Immunopharmacology
Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Behcet's disease (BD) and recurrent aphthous stomatitis is Th1-associated, although Th2-association is also observed in patients with BD.Scandinavian Journal of Rheumatology

2005

Effects of lichen heteroglycans on proliferation and IL-10 secretion by rat spleen cells and IL-10 and TNF-α secretion by rat peritoneal macrophages in vitroPhytomedicine

2004

The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in lifeClinical and Experimental Immunology

2001

Expression of adhesion and activation molecules in human buccal epithelial cell lines and normal human buccal epithelium in situJournal of Oral Pathology and Medicine
Antibodies to thymic epithelium form part of the murine autoreactive repertoire.Developmental and Comparative Immunology

2000

Production of monoclonal antibodies.

1999

γδ T cells in Behcet's disease (BD) and recurrent aphthous stomatitis (RAS)Clinical and Experimental Immunology

1998

K21-antigenDevelopmental Immunology

1993

Dermatitis Herpetiformis‐an Autoimmune Disease due to Cross‐Reaction between Dietary Glutenin and Dermal Elastin?Scandinavian Journal of Immunology
Reciprocal changes in complement activity and immune-complex levels during plasma infusion in a C2-deficient SLE patientLupus
Evaluation of in vivo immune complex formation and complement activation in patients receiving intravenous streptokinaseClinical and Experimental Immunology

1992

Do adults with high gliadin antibody concentrations have subclinical gluten intolerance?Gut

1991

A flow cytometric assay for measuring complement receptor 1 (CR1) and the complement fragments C3d and C4d on erythrocytesJournal of Immunological Methods

Keywords for Specialisation:

Resolution of inflammation