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| Sigrún Sunna Skúladóttir | Assistant Professor | 5254951 | sigrunsunna [at] hi.is | Emergency nursing |
| Sigurdís Haraldsdóttir | Professor | sigurdis [at] hi.is | Molecular cancer genetics | |
| Sigurður Guðjónsson | Associate Professor | 5254551 | siggig [at] hi.is | Gender and finance |
| Sigurður Ingvarsson | Professor | 5855123 | siguring [at] hi.is | Genetics |
| Simon William Matthews | Research Assistant Professor | 5254696 | simonm [at] hi.is | Radiogenic isotopes |
| Skúlína Hlíf Kjartansdóttir | Adjunct Lecturer | shk [at] hi.is | Aritificial intelligence in education | |
| Snæbjörn Pálsson | Professor | 5254293 | snaebj [at] hi.is | Population genetics |
| Snædís Huld Björnsdóttir | Professor | 5254614 | snaedis [at] hi.is | Genetics |
| Soffía Auður Birgisdóttir | Research Professor | 4708042 | soffiab [at] hi.is | Gender studies |
| Sofiya Zahova | Director | 3545255 988 | zahova [at] hi.is | Indigenous languages |